Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Animal models of traumatic brain injury
- Y. Xiong, A. Mahmood, M. Chopp
- Medicine
- Nature Reviews Neuroscience
- 1 February 2013
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity both in civilian life and on the battlefield worldwide. Survivors of TBI frequently experience long-term disabling changes… Expand
VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain.
VEGF is a secreted mitogen associated with angiogenesis and is also a potent vascular permeability factor. The biological role of VEGF in the ischemic brain remains unknown. This study was undertaken… Expand
Therapeutic Benefit of Intravenous Administration of Bone Marrow Stromal Cells After Cerebral Ischemia in Rats
Background and Purpose— We tested the hypothesis that intravenous infusion of bone marrow derived-marrow stromal cells (MSCs) enter the brain and reduce neurological functional deficits after stroke… Expand
Intravenous Administration of Human Umbilical Cord Blood Reduces Behavioral Deficits After Stroke in Rats
- J. Chen, P. Sanberg, +5 authors M. Chopp
- Medicine
- Stroke
- 1 November 2001
Background and Purpose— Human umbilical cord blood cells (HUCBC) are rich in stem and progenitor cells. In this study we tested whether intravenously infused HUCBC enter brain, survive,… Expand
Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery
ObjectiveTo test the effect of IV-injected human bone marrow stromal cells (hMSC) on neurologic functional deficits after stroke in rats. Methods Rats were subjected to transient middle cerebral… Expand
Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation
- M. Chopp, X. H. Zhang, +5 authors M. Rosenblum
- Medicine
- Neuroreport
- 11 September 2000
We tested the hypothesis that transplantation of bone marrow stromal cells (MSCs) into the spinal cord after a contusion injury promotes functional outcome. Rats (n = 31) were subjected to a weight… Expand
Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia
- R. L. Zhang, Z. Zhang, L. Zhang, M. Chopp
- Biology, Medicine
- Neuroscience
- 16 July 2001
Progenitor cells in the subventricular zone of the lateral ventricle and in the dentate gyrus of the hippocampus can proliferate throughout the life of the animal. To examine the proliferation and… Expand
Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat
- J. Chen, Y. Li, +6 authors M. Chopp
- Biology, Medicine
- Journal of neuroscience research
- 15 September 2003
The present study investigates the induction of neurogenesis, reduction of apoptosis, and promotion of basic fibroblast growth factor (bFGF) expression as possible mechanisms by which treatment of… Expand
Intravenous Administration of Human Bone Marrow Stromal Cells Induces Angiogenesis in the Ischemic Boundary Zone After Stroke in Rats
Abstract— We tested the hypothesis that intravenous infusion of human bone marrow stromal cells (hMSCs) promotes vascular endothelial growth factor (VEGF) secretion, VEGF receptor 2 (VEGFR2)… Expand
Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic
Restorative cell-based and pharmacological therapies for experimental stroke substantially improve functional outcome. These therapies target several types of parenchymal cells (including neural stem… Expand
...
1
2
3
4
5
...