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GRM1 wt Allele

Known as: MGLUR1, SCAR13, Protein Phosphatase 1, Regulatory Subunit 85 Gene 
Human GRM1 wild-type allele is located within 6q24 and is approximately 410 kb in length. This allele, which encodes metabotropic glutamate receptor… 
National Institutes of Health

Related topics

Related topics

11 relations
6q24G Protein-Coupled Receptor SignalingHomo sapiensLigand Binding

Broader (1)

GRM1 gene

Papers overview

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Highly Cited
2006
Highly Cited
2006
Predicting Compound Selectivity by Self‐Organizing Maps: Cross‐Activities of Metabotropic Glutamate Receptor Antagonists
The self-organizing map (SOM) principle was introduced by Kohonen in 1982, and has been applied to a variety of tasks in… 
2006
2006
Induction of Bcl-2 by functional regulation of G-protein coupled receptors protects from oxidative glutamate toxicity by increasing glutathione
Glutamate treatment depletes hippocampal HT22 cells of glutathione, which renders the cells incapable to reduce reactive oxygen… 
2005
2005
Sub‐neurotoxic neonatal anoxia induces subtle behavioural changes and specific abnormalities in brain group‐I metabotropic glutamate receptors in rats
Anoxia in the first week of life can induce neuronal death in vulnerable brain regions usually associated with an impairment of… 
Highly Cited
2005
Highly Cited
2005
Effects of mGlu1 and mGlu5 receptor antagonists on negatively reinforced learning
Effects on aversive learning of the novel highly selective mGlu5 receptor antagonist [(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine… 
2004
2004
Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors.
Highly Cited
2002
Highly Cited
2002
Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission: a mechanism for the attenuation of post-ischemic injury and epileptiform activity?
2002
2002
Type I and II metabotropic glutamate receptors modulate periaqueductal grey glycine release: interaction between mGlu2/3 and A1 adenosine receptors
2002
2002
Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo
Highly Cited
2001
Highly Cited
2001
Synthesis and biological evaluation of 2-(3'-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist.
Highly Cited
1999
Highly Cited
1999
A simple method to transfer plasmid DNA into neuronal primary cultures: functional expression of the mGlu5 receptor in cerebellar granule cells
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