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GRIN2A protein, human

Known as: N-Methyl-D-Aspartate Receptor Subunit 2A, NMDAR2A, Glutamate [NMDA] Receptor Subunit Epsilon-1 
Glutamate receptor ionotropic, NMDA 2A (1464 aa, ~165 kDa) is encoded by the human GRIN2A gene. This protein is involved in the modulation of ion… 
National Institutes of Health

Related topics

Related topics

19 relations
Alzheimer's Disease Pathway KEGGCellular MembraneGRIN2A geneGRIN2A wt Allele

Broader (1)

N-methyl D-aspartate receptor subtype 2A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
miR-501-3p mediates the activity-dependent regulation of the expression of AMPA receptor subunit GluA1
Expression of the Gria1-targeting miRNA miR-501-3p is increased locally in dendrites after NMDAR activation and is required for… 
Highly Cited
2006
Highly Cited
2006
Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition
Highly Cited
2005
Highly Cited
2005
CaMKIIα enhances the desensitization of NR2B-containing NMDA receptors by an autophosphorylation-dependent mechanism
Highly Cited
2003
Highly Cited
2003
Regulation of proteins affecting NMDA receptor-induced excitotoxicity in a Huntington's mouse model.
Symptoms of Huntington's disease may be caused by a toxic insult triggered by the mutant human huntingtin (Htt) protein itself… 
Highly Cited
2000
Highly Cited
2000
Regulation of Long-Term Potentiation by H-Ras through NMDA Receptor Phosphorylation
The proto-oncogene ras plays a critical role in cell proliferation and differentiation. However, ras genes are abundantly… 
Highly Cited
1999
Highly Cited
1999
NMDAR-2A subunit protein expression is reduced in the hippocampus of rats exposed to Pb2+ during development.
Highly Cited
1999
Highly Cited
1999
Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated [Ca2+]i increases and NMDA receptor mRNA levels
Highly Cited
1998
Highly Cited
1998
Attenuation of Focal Ischemic Brain Injury in Mice Deficient in the ε1 (NR2A) Subunit of NMDA Receptor
The role of glutamate neurotoxicity in cerebral ischemia has long been advocated but still remains controversial, because various… 
Highly Cited
1998
Highly Cited
1998
Effect of prenatal ethanol exposure on the developmental profile of the NMDA receptor subunits in rat forebrain and hippocampus.
The effects of prenatal ethanol exposure on the NMDAR1 protein expression (postnatal days 1 and 7) and on the developmental… 
Highly Cited
1996
Highly Cited
1996
Cellular distribution of the NMDA receptor NR2A/2B subunits in the rat striatum
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