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GRIN2A wt Allele

Known as: Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A wt Allele, NMDAR2A, EPND 
Human GRIN2A wild-type allele is located in the vicinity of 16p13.2 and is approximately 429 kb in length. This allele, which encodes glutamate… 
National Institutes of Health

Related topics

Related topics

10 relations
Alzheimer's Disease Pathway KEGGGRIN2A protein, humanHomo sapiensIonophore activity

Broader (1)

GRIN2A gene

Papers overview

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Highly Cited
2013
Highly Cited
2013
GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction
Epileptic encephalopathies are severe brain disorders with the epileptic component contributing to the worsening of cognitive and… 
Review
2009
Review
2009
Zinc in the physiology and pathology of the CNS
The past few years have witnessed dramatic progress on all frontiers of zinc neurobiology. The recent development of powerful… 
Highly Cited
1999
Highly Cited
1999
PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A.
Fyn, a member of the Src-family protein-tyrosine kinase (PTK), is implicated in learning and memory that involves N-methyl-D… 
Highly Cited
1997
Highly Cited
1997
Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro.
The interaction of Ro 25-6981 with N-methyl-D-aspartate (NMDA) receptors was characterized by a variety of different tests in… 
Highly Cited
1995
Highly Cited
1995
Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit.
The NMDA (N-methyl-D-aspartate) receptor channel is important for synaptic plasticity, which is thought to underlie learning… 
Highly Cited
1994
Highly Cited
1994
The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1
Neuronal plasticity associated with learning, memory and development is controlled, in part, by NMDA receptors, which are… 
Highly Cited
1994
Highly Cited
1994
Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death
Highly Cited
1994
Highly Cited
1994
The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition
The relationship between four pharmacologically distinct NMDA receptor subtypes, identified in radioligand binding studies, and… 
Highly Cited
1993
Highly Cited
1993
Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.
The effects of the atypical N-methyl-D-aspartate (NMDA) receptor antagonist ifenprodil were investigated by voltage-clamp… 
Highly Cited
1993
Highly Cited
1993
Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
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