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GPRC5A gene

Known as: G Protein-Coupled Receptor Class C Group 5 Member A Gene, RAIG1, GPRC5A 
This gene plays a role in G protein-coupled receptor signal transduction and is purported to play a role in embryonic development and epithelial… 
National Institutes of Health

Related topics

Related topics

8 relations
Embryonic DevelopmentG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingLigand Binding

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GPRC5A wt Allele

Papers overview

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Highly Cited
2018
Highly Cited
2018
Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis
Hypoxia is a hallmark of solid tumours and a key physiological feature distinguishing cancer from normal tissue. However, a major… 
Highly Cited
2015
Highly Cited
2015
Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling.
GPRC5A is a G-protein-coupled receptor expressed in lung tissue but repressed in most human lung cancers. Studies in Gprc5a… 
Highly Cited
2014
Highly Cited
2014
MiR-103a-3p targets the 5′ UTR of GPRC5A in pancreatic cells
There has been incremental evidence of miRNA binding sites not only being restricted to the 3′ UTR of mRNAs, but being… 
Review
2014
Review
2014
The emerging roles of GPRC5A in diseases
The ‘Retinoic Acid-Inducible G-protein-coupled receptors’ or RAIG are a group comprising the four orphan receptors GPRC5A, GPRC5B… 
Highly Cited
2009
Highly Cited
2009
Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice
G-protein-coupled receptors (GPCRs) constitute the largest family of transmembrane receptors and regulate a variety of… 
Highly Cited
2005
Highly Cited
2005
Promoter Hypermethylation as an Independent Prognostic Factor for Relapse in Patients with Prostate Cancer Following Radical Prostatectomy
Purpose: To analyze the prognostic significance of six epigenetic biomarkers (APC, Cyclin D2, GSTP1, TIG1, Rassf1A, and RARβ2… 
Highly Cited
2005
Highly Cited
2005
An inflammatory role for the mammalian carboxypeptidase inhibitor latexin: relationship to cystatins and the tumor suppressor TIG1.
2005
2005
Normal lung development in RAIG1-deficient mice despite unique lung epithelium-specific expression.
RAIG1, 2, and 3 and GPCR5d represent a new subfamily of orphan G protein-coupled receptors. RAIG1 is expressed abundantly and… 
2002
2002
Localisation of the GPRC5B receptor in the rat brain and spinal cord.
Highly Cited
2001
Highly Cited
2001
Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D.
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