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The Molecular Taxonomy of Primary Prostate Cancer

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ERG Status Is Unrelated to PSA Recurrence in Radically Operated Prostate Cancer in the Absence of Antihormonal Therapy

The striking similarities between these two types of prostate cancers rules out a major impact of ERG on tumor aggressiveness in early, not hormonally treated cancer and supports a systematic difference in potential response to hormonal therapy.
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Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer.

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Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer.

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CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer.

This study establishes CHD1 as the 5q21 tumor suppressor gene in prostate cancer and shows a key role of this chromatin remodeling factor in prostatecancer biology.
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Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) increases nerve-sparing frequency and reduces positive surgical margins in open and robot-assisted laparoscopic radical…

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Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study.

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Patterns of somatic structural variation in human cancer genomes

Whole-genome sequencing data from more than 2,500 cancers of 38 tumour types reveal 16 signatures that can be used to classify somatic structural variants, highlighting the diversity of genomic rearrangements in cancer.
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Clinical Utility of Quantitative Gleason Grading in Prostate Biopsies and Prostatectomy Specimens.

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Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer.

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