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GMP synthase (glutamine hydrolysing)
Known as:
GMP Synthetase
, GMP Synthase [Glutamine-Hydrolyzing]
, Glutamine Amidotransferase
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GMP synthase [glutamine-hydrolyzing] (693 aa, ~77 kDa) is encoded by the human GMPS gene. This protein plays a role in the biosynthesis of guanine…
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National Institutes of Health
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Related topics
Related topics
9 relations
Cytoplasm
Enzyme Gene
GMP synthase (glutamine-hydrolysing) activity
GMPS gene
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Broader (2)
GMP synthase
Ligase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
The Rice R2R3-MYB Transcription Factor OsMYB55 Is Involved in the Tolerance to High Temperature and Modulates Amino Acid Metabolism
A. El-kereamy
,
Y. Bi
,
Kosala Ranathunge
,
P. Beatty
,
A. Good
,
S. Rothstein
PLoS ONE
2012
Corpus ID: 36965505
Temperatures higher than the optimum negatively affects plant growth and development. Tolerance to high temperature is a complex…
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Highly Cited
2009
Highly Cited
2009
Glucosinolate engineering identifies a gamma-glutamyl peptidase.
F. Geu-Flores
,
M. T. Nielsen
,
+4 authors
B. Halkier
Nature Chemical Biology
2009
Corpus ID: 37120610
Consumption of cruciferous vegetables is associated with reduced risk of developing cancer, a phenomenon attributed to…
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Highly Cited
2003
Highly Cited
2003
The Crystal Structure of DJ-1, a Protein Related to Male Fertility and Parkinson's Disease*
K. Honbou
,
N. Suzuki
,
+4 authors
F. Inagaki
Journal of Biological Chemistry
2003
Corpus ID: 45296512
DJ-1 is a multifunctional protein that plays essential roles in tissues with higher order biological functions such as the testis…
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Highly Cited
1999
Highly Cited
1999
The crystal structure of anthranilate synthase from Sulfolobus solfataricus: functional implications.
Thorsten Knöchel
,
A. Ivens
,
+5 authors
J. Jansonius
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 17121457
Anthranilate synthase catalyzes the synthesis of anthranilate from chorismate and glutamine and is feedback-inhibited by…
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Highly Cited
1997
Highly Cited
1997
Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site.
J. Krahn
,
J. Kim
,
M. Burns
,
R. Parry
,
H. Zalkin
,
Janet L. Smith
Biochemistry
1997
Corpus ID: 33709480
Activation of gluatmine phosphoribosylpyrophosphate (RPPP) amidotransferase (GPATase) by binding of a PRPP substrate analog…
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Highly Cited
1996
Highly Cited
1996
The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families
J. Tesmer
,
T. Klem
,
M. Deras
,
V. Davisson
,
Janet L. Smith
Nature Structural Biology
1996
Corpus ID: 30864133
The crystal structure of GMP synthetase serves as a prototype for two families of metabolic enzymes. The Class I glutamine…
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Highly Cited
1993
Highly Cited
1993
Synthesis of 2,4-disubstituted thiazoles and selenazoles as potential antifilarial and antitumor agents. 2. 2-Arylamido and 2-alkylamido derivatives of 2-amino-4-(isothiocyanatomethyl)thiazole and 2…
Y. Kumar
,
R. Green
,
D. Wise
,
L. Wotring
,
Leroy B. Townsend
Journal of Medicinal Chemistry
1993
Corpus ID: 27657605
The synthesis of a series of 2-arylamido and 2-alkylamido derivatives of 2-amino-4-(isothiocyanatomethyl)thiazole and 2-amino-4…
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Highly Cited
1991
Highly Cited
1991
DegS-DegU and ComP-ComA modulator-effector pairs control expression of the Bacillus subtilis pleiotropic regulatory gene degQ
T. Msadek
,
F. Kunst
,
A. Klier
,
G. Rapoport
,
Unite de Biochimie Microbienne
Journal of Bacteriology
1991
Corpus ID: 32800151
Production of a class of both secreted and intracellular degradative enzymes in Bacillus subtilis is regulated at the…
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Highly Cited
1990
Highly Cited
1990
An apparent Bacillus subtilis folic acid biosynthetic operon containing pab, an amphibolic trpG gene, a third gene required for synthesis of para-aminobenzoic acid, and the dihydropteroate synthase…
J. Slock
,
D. P. Stahly
,
C. Han
,
E. Six
,
I. Crawford
Journal of Bacteriology
1990
Corpus ID: 2869655
McDonald and Burke (J. Bacteriol. 149:391-394, 1982) previously cloned a sulfanilamide-resistance gene, sul, residing on a 4.9-kb…
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Highly Cited
1982
Highly Cited
1982
Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193).
H. Jayaram
,
R. L. Dion
,
+4 authors
D. Cooney
Biochemical Pharmacology
1982
Corpus ID: 46267571
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