GMNN gene

Known as: geminin, DNA replication inhibitor, GEMININ, Gem 
This gene plays a role in DNA replication regulation.
National Institutes of Health

Papers overview

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2012
2012
Genomic changes frequently occur in cancer cells during tumorigenesis from normal cells. Using the Illumina Human NS-12 single… (More)
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2008
2008
Endoreplicating cells undergo multiple rounds of DNA replication leading to polyploidy or polyteny. Oscillation of Cyclin E (CycE… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Gene expression profiling data for human primary cutaneous melanomas are scarce because of the lack of retrospective… (More)
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2005
2005
Mcm2–7 (MCM) proteins are part of the origin licensing machinery that regulates initiation of DNA replication. Geminin is a… (More)
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Review
2004
Review
2004
Eukaryotic genomes are replicated from large numbers of replication origins distributed on multiple chromosomes. The activity of… (More)
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Highly Cited
2004
Highly Cited
2004
Organogenesis in vertebrates requires the tight control of cell proliferation and differentiation. The homeobox-containing… (More)
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Highly Cited
2004
Highly Cited
2004
Licensing of replication origins is carefully regulated in a cell cycle to maintain genome integrity. Using an in vivo… (More)
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Highly Cited
2002
Highly Cited
2002
Alteration of the control of DNA replication and mitosis is considered to be a major cause of genome instability. To investigate… (More)
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Highly Cited
2001
Highly Cited
2001
A hypomorphic mutation made in the ORC2 gene of a human cancer cell line through homologous recombination decreased Orc2 protein… (More)
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Highly Cited
2000
Highly Cited
2000
In all eukaryotic organisms, inappropriate firing of replication origins during the G2 phase of the cell cycle is suppressed by… (More)
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