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GMNN gene

Known as: geminin, DNA replication inhibitor, GEMININ, Gem 
This gene plays a role in DNA replication regulation.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND Gene expression profiling data for human primary cutaneous melanomas are scarce because of the lack of retrospective… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: The origin licensing factors minichromosome maintenance 2 (Mcm2) and Geminin have recently been identified as critical… Expand
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Highly Cited
2005
Highly Cited
2005
Mcm2–7 (MCM) proteins are part of the origin licensing machinery that regulates initiation of DNA replication. Geminin is a… Expand
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Review
2004
Review
2004
Eukaryotic genomes are replicated from large numbers of replication origins distributed on multiple chromosomes. The activity of… Expand
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Highly Cited
2004
Highly Cited
2004
Organogenesis in vertebrates requires the tight control of cell proliferation and differentiation. The homeobox-containing… Expand
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Highly Cited
2004
Highly Cited
2004
Licensing of replication origins is carefully regulated in a cell cycle to maintain genome integrity. Using an in vivo… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Genomic DNA replication is tightly controlled to ensure that DNA replication occurs once per cell cycle; loss of this… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Alteration of the control of DNA replication and mitosis is considered to be a major cause of genome instability. To… Expand
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Highly Cited
2001
Highly Cited
2001
A hypomorphic mutation made in the ORC2 gene of a human cancer cell line through homologous recombination decreased Orc2 protein… Expand
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Highly Cited
2000
Highly Cited
2000
In all eukaryotic organisms, inappropriate firing of replication origins during the G2 phase of the cell cycle is suppressed by… Expand
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