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GLO1 gene

Known as: GLOD1, GLYOXALASE I, GLO1 
National Institutes of Health

Related topics

Related topics

2 relations
Lactoylglutathione Lyaseglyoxalase I activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology
Aims/hypothesisMethylglyoxal (MG) is an important precursor for AGEs. Normally, MG is detoxified by the glyoxalase (GLO) enzyme… 
Highly Cited
2012
Highly Cited
2012
Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal.
Glyoxalase 1 (Glo1) expression has previously been associated with anxiety in mice; however, its role in anxiety is controversial… 
Highly Cited
2011
Highly Cited
2011
Potential contribution of oxidative stress and inflammation to anxiety and hypertension
Highly Cited
2010
Highly Cited
2010
Enhanced carbonyl stress in a subpopulation of schizophrenia.
CONTEXT Various factors are involved in the pathogenesis of schizophrenia. Accumulation of advanced glycation end products… 
Highly Cited
2010
Highly Cited
2010
GLO1—A novel amplified gene in human cancer
To identify a novel amplified cancer gene a systematic screen of 975 human cancer DNA samples, 750 cell lines and 225 primary… 
Highly Cited
2010
Highly Cited
2010
Expression of antimicrobial peptide genes in Bombyx mori gut modulated by oral bacterial infection and development.
Highly Cited
2008
Highly Cited
2008
Curcumin Inhibits Glyoxalase 1—A Possible Link to Its Anti-Inflammatory and Anti-Tumor Activity
Background Glyoxalases (Glo1 and Glo2) are involved in the glycolytic pathway by detoxifying the reactive methylglyoxal (MGO… 
Highly Cited
2008
Highly Cited
2008
Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress.
Protection of mitochondrial proteins from glycation by endogenous dicarbonyl compounds, methylglyoxal and glyoxal, was found… 
Highly Cited
2008
Highly Cited
2008
The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I
Osteoclasts, bone-resorptive multinucleated cells derived from hematopoietic stem cells, are associated with many bone-related… 
Highly Cited
1983
Highly Cited
1983
EXTENDED MHC HAPLOTYPES IN 21-HYDROXYLASE-DEFICIENCY CONGENITAL ADRENAL HYPERPLASIA: SHARED GENOTYPES IN UNRELATED PATIENTS
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