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Stability of tea polyphenol (-)-epigallocatechin-3-gallate and formation of dimers and epimers under common experimental conditions.
The results demonstrated that auto-oxidation and epimerization are the two major reactions causing the instability of EGCG.
Antioxidative Phenolic Compounds from Sage (Salvia officinalis)
Ten phenolic compounds were isolated from a butanol fraction of sage extracts. Their structures were determined by spectral methods (NMR, MS, IR). Among them, a novel compound,
Effective inhibition of MERS-CoV infection by resveratrol
It is perceived that resveratrol can be a potential antiviral agent against MERS-CoV infection in the near future.
Antioxidant Activities of Caffeic Acid and Its Related Hydroxycinnamic Acid Compounds
Hydroxycinnamic acid compounds are an important source of antioxidants due to their ubiquitous occurrence in the plant kingdom and their characteristic activities. In this study, we compared the
Glucuronides of tea catechins: enzymology of biosynthesis and biological activities.
The glucuronidation of EGCG and EGC in human, mouse, and rat microsomes and by nine different human UGT 1A and 2B isozymes expressed in insect cells is characterized to provide foundations for understanding the biotransformation and biological activities of tea catechins.
Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-kappaB in mouse macrophages.
The results suggest that carnosol suppresses the NO production and iNOS gene expression by inhibiting NF-kappaB activation, and provide possible mechanisms for its anti-inflammatory and chemopreventive action.
Anti-inflammatory activity of natural dietary flavonoids.
Current knowledge and underlying mechanisms on anti-inflammatory activities of flavonoids and their implicated effects in the development of various chronic inflammatory diseases are summarized.