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glyoxalase I activity

Known as: aldoketomutase activity, (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming), (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity 
Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal. [EC:4.4.1.5, RHEA:19072]
National Institutes of Health

Related topics

Related topics

3 relations
GLO1 geneLactoylglutathione Lyaseglyoxylase I

Papers overview

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2009
2009
A swelling improving agent comprising S-lactoyl glutathione and / or a salt thereof.
1993
1993
The hydrolysis of S-D-lactoylglutathione.
S-o-Lactoylglutathione is a thioester derivative. It is the physiological intermediate of the glyoxalase system and is present in… 
1993
1993
The effect of S-D-lactoylglutathione on the movement of neutrophils.
1993
1993
The potentiation of GTP-dependent assembly of microtubules by S-D-lactoylglutathione.
Review
1988
Review
1988
[Glyoxalase I and its application to production of S-lactoylglutathione].
1982
1982
Fluorescence and nuclear relaxation enhancement studies of the binding of glutathione derivatives to manganese-reconstituted glyoxalase I from human erythrocytes. A model for the catalytic mechanism…
The apoenzyme of glyoxalase I (EC 4.4.1.5) from human erythrocytes was prepared by removal of Zn2+ with… 
1981
1981
13-Hydroperoxylinoleic acid inhibits rat liver glyoxalase II
Abstract13-Hydroperoxylinoleic acid (13-HPLA) inhibited glyoxalase II in rat liver supernatants with half the maximum inhibition… 
1978
1978
Concanavalin A increases glyoxalase enzyme activities in polymorphonuclear leukocytes and lymphocytes.
Glyoxalase I converts methylglyoxal and glutathione to S-lactoylglutathione and glyoxalase II converts this compound to D-lactic…