Lactoylglutathione Lyase

Known as: Lactoylglutathione Lyase [Chemical/Ingredient], Methylglyoxalase, Glyoxalase 
An enzyme that catalyzes the interconversion of methylglyoxal and lactate, with glutathione serving as a coenzyme. EC 4.4.1.5.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Hyperglycemia-mediated oxidative stress plays a crucial role in the progression of diabetic nephropathy. Hence, the present study… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE RAGE interacts with the endogenous ligands S100 calgranulins and high mobility group box 1 (HMGB1) to induce… (More)
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Review
2010
Review
2010
Methylglyoxal (MG) is a potent protein glycating agent. Glycation is directed to guanidino groups of arginine residues forming… (More)
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Highly Cited
2005
Highly Cited
2005
Anxiety and fear are normal emotional responses to threatening situations. In human anxiety disorders—such as panic disorder… (More)
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Highly Cited
1999
Highly Cited
1999
Methylglyoxal (MG) is a reactive alpha-dicarbonyl that is thought to contribute to diabetic complications either as a direct… (More)
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Highly Cited
1998
Highly Cited
1998
Methylglyoxal (MG), a dicarbonyl compound produced by the fragmentation of triose phosphates, forms advanced glycation… (More)
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Review
1998
Review
1998
The glyoxalase system is a metabolic pathway that catalyses the detoxification of alpha-oxoaldehydes RCOCHO to corresponding… (More)
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Review
1996
Review
1996
1. Methylglyoxal is a reactive alpha-oxoaldehyde and physiological metabolite formed by the fragmentation of triose-phosphates… (More)
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Highly Cited
1994
Highly Cited
1994
1. The metabolism of methylglyoxal by the glyoxalase system may be linked to the development of diabetic complications. The… (More)
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Review
1990
Review
1990
The glyoxalase system catalyses the conversion of methylglyoxal to D-lactic acid via the intermediate S-D-lactoylglutathione (Fig… (More)
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