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GJA1 protein, human

Known as: Connexin 43, gap junction protein, alpha 1, 43kDa (connexin 43) protein, human, connexin 43 protein, human 
Gap junction alpha-1 protein (382 aa, ~43 kDa) is encoded by the human GJA1 gene. This protein is involved in the regulation of the assembly of gap… 
National Institutes of Health

Related topics

Related topics

13 relations
Beta-Catenin Accumulation PathwayCellular MembraneGJA1 geneGap Junctions

Broader (1)

Connexin 43

Papers overview

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Highly Cited
2011
Highly Cited
2011
Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1
Cx43 gap junctions (GJs) are integral to the function of the mammalian heart. It is shown that ZO-1 dynamically regulates the… 
Review
2010
Review
2010
Implications and challenges of connexin connections to cancer
The idea that the gap junction family of proteins, connexins, are tumour suppressors has been widely supported through numerous… 
Highly Cited
2007
Highly Cited
2007
Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells.
Highly Cited
2004
Highly Cited
2004
Ubiquitination and Down-regulation of Gap Junction Protein Connexin-43 in Response to 12-O-Tetradecanoylphorbol 13-Acetate Treatment*
Gap junctions are specialized plasma membrane domains enriched in connexin proteins that form channels between adjacent cells… 
Highly Cited
2002
Highly Cited
2002
Casein Kinase 1 Regulates Connexin-43 Gap Junction Assembly*
Phosphorylation of members of the connexin family of gap junction proteins has been correlated with gap junction assembly, but… 
Highly Cited
2001
Highly Cited
2001
Interaction of c-Src with Gap Junction Protein Connexin-43
Cell-cell communication via connexin-43 (Cx43)-based gap junctions is transiently inhibited by certain mitogens, but the… 
Highly Cited
2001
Highly Cited
2001
c-Src Regulates the Interaction between Connexin-43 and ZO-1 in Cardiac Myocytes*
Connexin-43 is known to interact directly with ZO-1 in cardiac myocytes, but little is known about the role of ZO-1 in connexin… 
Highly Cited
2000
Highly Cited
2000
The ε Subtype of Protein Kinase C Is Required for Cardiomyocyte Connexin-43 Phosphorylation
Abstract —Gap junctions (GJs), composed of connexins, are intercellular channels ensuring electric and metabolic coupling between… 
Highly Cited
1998
Highly Cited
1998
Direct Association of the Gap Junction Protein Connexin-43 with ZO-1 in Cardiac Myocytes*
The gap junction protein connexin-43 is normally located at the intercalated discs of cardiac myocytes, and it plays a critical… 
Highly Cited
1994
Highly Cited
1994
Expression of the gap junction protein connexin-43 is increased in the human myometrium toward term and with the onset of labor.
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