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GJA1 protein, human

Known as: Connexin 43, gap junction protein, alpha 1, 43kDa (connexin 43) protein, human, connexin 43 protein, human 
Gap junction alpha-1 protein (382 aa, ~43 kDa) is encoded by the human GJA1 gene. This protein is involved in the regulation of the assembly of gap… 
National Institutes of Health

Related topics

Related topics

13 relations
Beta-Catenin Accumulation PathwayCellular MembraneGJA1 geneGap Junctions

Broader (1)

Connexin 43

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Synergism between arrhythmia and hyperhomo-cysteinemia in structural heart disease.
Elevated levels of homocysteine (Hcy) known as hyperhomocysteinemia (HHcy) is associated with cardiac arrhythmia and sudden… 
2005
2005
Inhibition of connexin 43 alters Shh and Bmp-2 expression patterns in embryonic mouse tongue
The morphogenesis of fungiform papillae occurs in a stereotyped pattern on the dorsal surface of the mammalian tongue via… 
2005
2005
Human Marrow Stromal Cells Enhance Connexin43 Gap Junction Intercellular Communication in Cultured Astrocytes
Human marrow stromal cells (hMSCs) provide functional benefit in rats subjected to stroke. Astrocytes are coupled into a cellular… 
2005
2005
Intraperitoneal infusion of proinflammatory cytokines does not cause activation of the rat uterus during late gestation.
Increased concentrations of IL-1beta and TNF-alpha have been associated with parturition. However, the role of these cytokines is… 
2001
2001
Enhanced apoptosis under low serum conditions in human glioblastoma cells by connexin 43 (Cx43)
Connexin 43 (Cx43), a structural component of gap junctions, is believed to function as a tumor suppressor gene. Previously, we… 
2000
2000
Growth Hormone Increases Connexin-43 Expression in the Cerebral Cortex and Hypothalamus.
Several studies indicate that systemic GH influences various brain functions. Connexin-43 forms gap junctions that mediate… 
1998
1998
Hormonal regulation of connexin-43 in baboon corpora lutea.
The synthesis and secretion of progesterone in the corpus luteum are regulated by both endocrine and paracrine/ autocrine factors… 
1997
1997
Gamma linolenic acid regulates gap junction communication in endothelial cells and their interaction with tumour cells.
1995
1995
Inhibition of Glycosylation Induces Formation of Open Connexin-43 Cell-to-Cell Channels and Phosphorylation and Triton X-100 Insolubility of Connexin-43 (*)
We transfected the cDNA for the cell-to-cell channel protein connexin-43 (Cx43) into Morris hepatoma H5123 cells, which express… 
Highly Cited
1994
Highly Cited
1994
Lysophosphatidic acid inhibits gap-junctional communication and stimulates phosphorylation of connexin-43 in WB cells: possible involvement of the mitogen-activated protein kinase cascade.
Lysophosphatidic acid (LPA) was shown to be a powerful inhibitor of gap-junctional communication between cultured rat liver WB… 
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