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Gap Junctions

Known as: macula communicans, Low-resistance Junction, Communicating cell junction 
A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions… 
National Institutes of Health

Related topics

Related topics

18 relations
Cell surfaceConnexinsConnexonElectrical Synapses

Broader (2)

Intercellular Junctionsintercellular connection

Narrower (1)

connexon complex location

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.
More than 130 different mutations in the gap junction integral plasma membrane protein connexin32 (Cx32) have been linked to the… 
Highly Cited
1995
Highly Cited
1995
pp60src -mediated Phosphorylation of Connexin 43, a Gap Junction Protein (*)
Several laboratories have demonstrated a decrease in gap junctional communication in cells transformed by the src oncogene of the… 
Highly Cited
1993
Highly Cited
1993
Multiple connexins colocalize in canine ventricular myocyte gap junctions.
We have recently shown that adult canine ventricular myocytes express three distinct gap junction channel proteins, connexin40… 
Highly Cited
1991
Highly Cited
1991
Functional analysis of human cardiac gap junction channel mutants.
The connexins form a family of membrane spanning proteins that assemble into gap junction channels. The biophysical properties of… 
Review
1990
Review
1990
Chemical, oncogene and growth factor inhibition gap junctional intercellular communication: an integrative hypothesis of carcinogenesis.
Most, if not all, cancer cells have some dysfunction in gap-junction-mediated intercellular communication, either because of… 
Highly Cited
1987
Highly Cited
1987
Proteoglycans and glycosaminoglycans induce gap junction synthesis and function in primary liver cultures
Intercellular communication via gap junctions, as measured by dye and electrical coupling, disappears within 12 h in primary rat… 
Highly Cited
1979
Highly Cited
1979
Oocyte-follicle cell gap junctions in Xenopus laevis and the effects of gonadotropin on their permeability.
Junctions between Xenopus laevis oocytes and follicle cells have been identified as gap junctions by the passage of microinjected… 
Highly Cited
1977
Highly Cited
1977
Characterization of intercellular junctions in the preimplantation mouse embryo by freeze-fracture and thin-section electron microscopy.
Highly Cited
1976
Highly Cited
1976
Organization of intramembrane particles in freeze-cleaved gap junctions of rat graafian rollicles: optical-diffraction analysis.
Gap junctions were identified in the membrana granulosa and cumulus oophorus, and between cells of the internal theca, of the… 
Review
1971
Review
1971
Comparative ultrastructure of cellular junctions in working myocardium and the conduction system under normal and pathologic conditions.
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