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Gap Junctions

Known as: macula communicans, Low-resistance Junction, Communicating cell junction 
A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions… 
National Institutes of Health

Related topics

Related topics

18 relations
Cell surfaceConnexinsConnexonElectrical Synapses

Broader (2)

Intercellular Junctionsintercellular connection

Narrower (1)

connexon complex location

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.
More than 130 different mutations in the gap junction integral plasma membrane protein connexin32 (Cx32) have been linked to the… 
Highly Cited
2000
Highly Cited
2000
Regulation of Connexin Degradation as a Mechanism to Increase Gap Junction Assembly and Function*
Connexins, the integral membrane protein constituents of gap junctions, are degraded at a rate (t 1 2 = 1.5–5 h) much faster than… 
Highly Cited
1998
Highly Cited
1998
Individual gap junction plaques contain multiple connexins in arterial endothelium.
Gap-junctional intercellular communication in endothelial cells is implicated in the coordination of growth, migration, and… 
Highly Cited
1997
Highly Cited
1997
Degradation of connexin43 gap junctions involves both the proteasome and the lysosome.
Intercellular communication may be modulated by the rather rapid turnover and degradation of gap junction proteins, since many… 
Highly Cited
1995
Highly Cited
1995
pp60src -mediated Phosphorylation of Connexin 43, a Gap Junction Protein (*)
Several laboratories have demonstrated a decrease in gap junctional communication in cells transformed by the src oncogene of the… 
Highly Cited
1993
Highly Cited
1993
Multiple connexins colocalize in canine ventricular myocyte gap junctions.
We have recently shown that adult canine ventricular myocytes express three distinct gap junction channel proteins, connexin40… 
Highly Cited
1991
Highly Cited
1991
Functional analysis of human cardiac gap junction channel mutants.
The connexins form a family of membrane spanning proteins that assemble into gap junction channels. The biophysical properties of… 
Highly Cited
1989
Highly Cited
1989
Improved propagation in myometrium associated with gap junctions during parturition.
The hypothesis that gap junction (GJ) formation between myometrial cells at term improves electrical coupling was tested. We… 
Highly Cited
1987
Highly Cited
1987
Proteoglycans and glycosaminoglycans induce gap junction synthesis and function in primary liver cultures
Intercellular communication via gap junctions, as measured by dye and electrical coupling, disappears within 12 h in primary rat… 
Highly Cited
1977
Highly Cited
1977
Characterization of intercellular junctions in the preimplantation mouse embryo by freeze-fracture and thin-section electron microscopy.
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