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GJA1 gene

Known as: ODOD, GAP JUNCTION PROTEIN, ALPHA-1, ODD 
This gene is involved in gap junction assembly.
National Institutes of Health

Related topics

Related topics

11 relations
Connexin 43GJA1 protein, humanGJA1P1 geneHomo sapiens

Papers overview

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Highly Cited
2016
Highly Cited
2016
Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer
Brain metastasis represents a substantial source of morbidity and mortality in various cancers, and is characterized by high… 
Highly Cited
2011
Highly Cited
2011
The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2
MicroRNAs (miRNAs) are endogenous noncoding RNAs, about 22 nucleotides in length, that mediate post-transcriptional gene… 
Highly Cited
2011
Highly Cited
2011
Astroglial networks scale synaptic activity and plasticity
Astrocytes dynamically interact with neurons to regulate synaptic transmission. Although the gap junction proteins connexin 30… 
Review
2009
Review
2009
GJA1 mutations, variants, and connexin 43 dysfunction as it relates to the oculodentodigital dysplasia phenotype
The predominantly autosomal dominant disorder, oculodentodigital dysplasia (ODDD) has high penetrance with intra‐ and… 
Highly Cited
2007
Highly Cited
2007
Gap junction adhesion is necessary for radial migration in the neocortex
Radial glia, the neuronal stem cells of the embryonic cerebral cortex, reside deep within the developing brain and extend radial… 
Highly Cited
2005
Highly Cited
2005
A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia
Oculodentodigital dysplasia (ODDD) is an autosomal dominant disorder characterized by pleiotropic developmental anomalies of the… 
Highly Cited
2003
Highly Cited
2003
Connexin 43 (GJA1) mutations cause the pleiotropic phenotype of oculodentodigital dysplasia.
Gap junctions are assemblies of intercellular channels that regulate a variety of physiologic and developmental processes through… 
Highly Cited
2003
Highly Cited
2003
Gating and regulation of connexin 43 (Cx43) hemichannels
Connexin 43 (Cx43) nonjunctional or “unapposed” hemichannels can open under physiological or pathological conditions. We… 
Highly Cited
2001
Highly Cited
2001
Connexin 43 hemichannels mediate Ca2+‐regulated transmembrane NAD+ fluxes in intact cells
A previously unrecognized passive transport for pyridine dinucleotides has been described recently in the plasmamembrane of… 
Highly Cited
1998
Highly Cited
1998
Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43).
Connexins (cx), structural components of gap junction, are believed to play a role in the regulation of cell proliferation and… 
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