Skip to search formSkip to main contentSkip to account menu

G1/S-Specific Cyclin-D3

Known as: CCND3, G1/S-Specific Cyclin D3 
G1/S-specific cyclin-D3 (292 aa, ~33 kDa) is encoded by the human CCND3 gene. This protein is involved in the progression of the cell cycle.
National Institutes of Health

Related topics

Related topics

12 relations
CCND3 geneCell CycleCell Cycle ControlCell Cycle Progression

Broader (1)

cyclin D3

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
MicroRNA miR-4779 suppresses tumor growth by inducing apoptosis and cell cycle arrest through direct targeting of PAK2 and CCND3
Depending on the function of their target genes, microRNAs (miRNAs) act as either tumor suppressors or oncogenes. Therefore… 
2016
2016
Cell-Cycle Gene Alterations in 4,864 Tumors Analyzed by Next-Generation Sequencing: Implications for Targeted Therapeutics
Alterations in the cyclin-dependent kinase (CDK)-retinoblastoma (RB) machinery disrupt cell-cycle regulation and are being… 
Highly Cited
2015
Highly Cited
2015
Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer
The interaction between tumor cells and their microenvironment is an essential aspect of tumor development. Therefore… 
2015
2015
Activation of TLR7 increases CCND3 expression via the downregulation of miR-15b in B cells of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by B-cell hyperreactivity. The Toll-like receptor 7… 
2015
2015
MiR-592 inhibited cell proliferation of human colorectal cancer cells by suppressing of CCND3 expression.
Accumulating evidence shows that microRNA (miRNA) is frequently associated with multiple kinds of human cancers, including… 
2014
2014
Alternative Splicing Is a Frequent Event and Impacts Clinical Outcome in Myeloma: A Large RNA-Seq Data Analysis of Newly-Diagnosed Myeloma Patients
Alternative splicing is an important post-translational change that alters gene function. Misregulation of alternative splicing… 
2012
2012
Translational repression of cyclin D3 by a stable G-quadruplex in its 5′ UTR: implications for cell cycle regulation
cyclin D3 (CCND3) is one of the three D-type cyclins that regulate the G1/S phase transition of the cell cycle. Expression of… 
2010
2010
Differential roles of cyclin D1 and D3 in pancreatic ductal adenocarcinoma
BackgroundThe cyclin D1 (CCND1) and cyclin D3 (CCND3) are frequently co-overexpressed in pancreatic ductal adenocarcinoma (PDAC… 
2009
2009
Polymorphic loci of E2F2, CCND1 and CCND3 are associated with HER2 status of breast tumors
Overexpression of the human epidermal growth factor receptor 2 (HER2) in breast tumors is associated with bad prognosis… 
2005
2005
Down-regulation of Cyclin D3 by Small-interfering RNA Induces Cell Cycle Arrest and Apoptosis through the Dissociation of p27Kip1 in a t(6 ; 14) (p21 ; q32) Positive Myeloma Cell Line
Translocation of chromosome t (6 ; 14) (p21 ; q32) results in overexpression of the cyclin D3 gene (CCND3), and is a recurrent… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)