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Fura-2

Known as: 5-Oxazolecarboxylic acid, 2-(6-(bis(carboxymethyl)amino)-5-(2-(2-(bis(carboxymethyl)amino)-5-methylphenoxy)ethoxy)-2-benzofuranyl)-, Fura 2, Fura-2 [Chemical/Ingredient] 
A fluorescent calcium chelating agent which is used to study intracellular calcium in tissues.
National Institutes of Health

Related topics

Related topics

16 relations

Narrower (6)

C18-fura-2fura Ffura-2-amfura-FFP18

Broader (2)

Calcium Chelating AgentsFluorescent Dyes
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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2013
2013
Endothelial Nitric Oxide Production in Preeclamptic Pregnancies
Approximately 8% of pregnancies are complicated by preeclampsia (PE), a hypertensive condition characterized by widespread… 
2004
2004
Spontaneous calcium oscillations and mechanically and chemically induced calcium responses in mammary epithelial cells
Changes of intracellular calcium activity (Cai2+) in mouse mammary epithelial cells in primary culture (normal) and in an… 
1997
1997
Lead Reduces Depolarization-Induced Calcium Entry in Cultured DRG Neurons Without Crossing the Cell Membrane: Fura-2 Measurements
Abstract1. Cultured dorsal root ganglion neurons of rat pups were depolarized by exposure to 50 mM K+ and the rise of [Ca2+]i was… 
1989
1989
Altered free cytosolic calcium changes and neutrophil chemotaxis in patients with juvenile periodontitis.
Nearly 70-75% of patients with localized juvenile periodontitis (JP) have abnormal polymorphonuclear leukocytic (PMN) chemotaxis… 
Highly Cited
1988
Highly Cited
1988
Conversion of esterified fura-2 and indo-1 to Ca2+-sensitive forms by mitochondria.
Rat liver mitochondria are shown to convert the acetoxymethyl ester forms of fura-2 and indo-1 into Ca2+-dependent forms of these… 
Highly Cited
1987
Highly Cited
1987
Receptor coupled events in bradykinin action: rapid production of inositol phosphates and regulation of cytosolic free Ca2+ in a neural cell line.
The addition of bradykinin to NG115‐401L cells grown on coverslips results in the generation of rapid transient increases in… 
1987
1987
Free calcium in isolated chick embryo heart cells measured using quin2 and fura-2.
Cytosolic free calcium (Cai) was measured using quin2 and fura-2 in isolated chick embryo heart cells. Account was taken of… 
Highly Cited
1987
Highly Cited
1987
Interrelationship between growth factor-induced pH changes and intracellular Ca2+.
Many mitogens cause rapid changes in intracellular pH and Ca2+. We studied the patterns of pH and Ca2+ changes after exposure of… 
1987
1987
Rapid intracellular calcium changes in U937 monocyte cell line: transient increases in response to platelet-activating factor and chemotactic peptide but not interferon-gamma or lipopolysaccharide.
The dye fura-2, a potentially more sensitive successor to quin2 for measuring intracellular free calcium ion concentrations [(Ca2… 
1983
1983
Relationship between antitumor effect and metabolites of 5-fluorouracil in combination treatment with 5-fluorouracil and guanosine in ascites sarcoma 180 tumor system.
The antitumor activity of 5-fluorouracil (FUra) against ascites Sarcoma 180 was significantly enhanced by coadministration of…