Fucosylated Umbilical Cord Blood Regulatory T Cells

Known as: Fucosylated UCB Tregs 
Fucosylated, human umbilical cord blood (UCB)-derived regulatory T-cells (Tregs), with potential immunomodulating activity. Ex vivo, Tregs are… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The microbiota regulates type 2 immunity through RORγt+ T cells
Changes to the symbiotic microbiota early in life, or the absence of it, can lead to exacerbated type 2 immunity and allergic… (More)
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Highly Cited
2013
Highly Cited
2013
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis.
Atherosclerosis is a chronic inflammatory disease promoted by hyperlipidemia. Several studies support FOXP3-positive regulatory T… (More)
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Highly Cited
2013
Highly Cited
2013
GPR15-mediated homing controls immune homeostasis in the large intestine mucosa.
Lymphocyte homing, which contributes to inflammation, has been studied extensively in the small intestine, but there is little… (More)
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Highly Cited
2010
Highly Cited
2010
Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice.
BACKGROUND & AIMS Foxp3+ T regulatory cells (Tregs) help prevent autoimmunity, and increases in their numbers of functions could… (More)
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Highly Cited
2009
Highly Cited
2009
Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells.
Foxp3 is a transcription factor that is essential for the normal development of regulatory T cells (Tregs). In the absence of… (More)
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Highly Cited
2009
Highly Cited
2009
CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2.
Regulatory T cells (Tregs) are engaged in the maintenance of immunological self-tolerance and immune homeostasis. IL-10 has an… (More)
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Highly Cited
2006
Highly Cited
2006
TNF downmodulates the function of human CD4+CD25hi T-regulatory cells.
CD4+CD25+ T-regulatory cells (Tregs) play an essential role in maintaining immunologic homeostasis and preventing autoimmunity… (More)
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Highly Cited
2005
Highly Cited
2005
A peripheral circulating compartment of natural naive CD4 Tregs.
CD4CD25 Tregs play a central role in the maintenance of peripheral self tolerance by keeping autoreactive T cells in check… (More)
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Highly Cited
2005
Highly Cited
2005
The IL-4 receptor alpha-chain-binding cytokines, IL-4 and IL-13, induce forkhead box P3-expressing CD25+CD4+ regulatory T cells from CD25-CD4+ precursors.
The mechanisms underlying the extrathymic generation of CD25+CD4 regulatory T cells (Tregs) are largely unknown. In this study… (More)
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Highly Cited
2002
Highly Cited
2002
Xyloglucan endotransglycosylases have a function during the formation of secondary cell walls of vascular tissues.
Xyloglucan transglycosylases (XETs) have been implicated in many aspects of cell wall biosynthesis, but their function in… (More)
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