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Flutamide

Known as: Propanamide, 2-Methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-, Niftolid, Flutamide [Chemical/Ingredient] 
A toluidine derivative and a nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Androgen-deprivation therapy (ADT) is a widely used treatment for prostate cancer. Recently, several studies have reported an… Expand
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Highly Cited
2006
Highly Cited
2006
Abstract The concentrations of 16 US-EPA criteria polycyclic aromatic hydrocarbons (PAHs) were monitored during various seasons… Expand
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Review
2005
Review
2005
Female and male brains differ. Differences begin early during development due to a combination of genetic and hormonal events and… Expand
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Highly Cited
2000
Highly Cited
2000
Polycystic ovarian syndrome (PCOS) is a complex disorder with multiple abnormalities, including hyperandrogenism, ovulatory… Expand
Highly Cited
1999
Highly Cited
1999
Gestational and lactational exposure to di(n-butyl) phthalate (DBP) at >/=250 mg/kg/day disrupts male rat reproductive… Expand
Highly Cited
1998
Highly Cited
1998
BACKGROUND Combined androgen blockade for the treatment of metastatic prostate cancer consists of an antiandrogen drug plus… Expand
Highly Cited
1993
Highly Cited
1993
  • H. Scher, W. Kelly
  • Journal of clinical oncology : official journal…
  • 1993
  • Corpus ID: 708525
PURPOSE To evaluate the effect of discontinuation of the antiandrogen, flutamide, in patients with metastatic prostate cancer who… Expand
Highly Cited
1992
Highly Cited
1992
The significance of apoptosis in relation to the development and progression of prostate cancer remains largely undefined. bcl-2… Expand
Highly Cited
1989
Highly Cited
1989
To test the hypothesis that maximal androgen blockade improves the effectiveness of the treatment of prostatic cancer, we… Expand
Highly Cited
1983
Highly Cited
1983
Prenatal treatment of male rats with the anti-androgen, flutamide (FL), demasculinizes the sexually dimorphic spinal nucleus of… Expand
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