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Flutamide

Known as: Propanamide, 2-Methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-, Niftolid, Flutamide [Chemical/Ingredient] 
A toluidine derivative and a nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent… 
National Institutes of Health

Related topics

Related topics

36 relations
AR protein, humanAndrogen Receptor Antagonists [MoA]CYP1A2 protein, humanDrug Allergy

Broader (3)

Androgen AntagonistsAntineoplastic AgentsAntineoplastic Agents, Hormonal

Narrower (7)

EulexinFlucinomFluta-GRYFlutan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Twenty‐four‐month postradiation prostate biopsies are strongly predictive of 7‐year disease‐free survival
The objective of this study was to evaluate the predictive value of prostate biopsies that were obtained 24 months after the… 
Highly Cited
2000
Highly Cited
2000
Adjuvant mitozantrone chemotherapy in advanced prostate cancer
Objective To assess the role of mitozantrone, active in relapsed prostate cancer, as an adjuvant to hormonal treatment in… 
Highly Cited
1999
Highly Cited
1999
Testosterone and its metabolites affect afterdischarge thresholds and the development of amygdala kindled seizures
Review
1997
Review
1997
The indications, rationale, and results of neoadjuvant androgen deprivation in the treatment of prostatic cancer: Memorial Sloan-Kettering Cancer Center results.
Highly Cited
1995
Highly Cited
1995
Insulin sensitivity and antiandrogenic therapy in women with polycystic ovary syndrome.
Highly Cited
1992
Highly Cited
1992
Flutamide‐induced regression of angiofibroma
Juvenile nasopharyngeal angiofibroma (JNA) appears to be an endocrine‐responsive tumor. This concept was tested in five young men… 
Highly Cited
1991
Highly Cited
1991
Identifying the recognition unit for G protein methylation.
Highly Cited
1980
Highly Cited
1980
Hormonal regulation of penile erection in castrated male rats
Highly Cited
1974
Highly Cited
1974
Action of a nonsteroidal antiandrogen, flutamide, on the receptor binding and nuclear retention of 5 alpha-dihydrotestosterone in rat ventral prostate.
The nonsteroidal anntiandrogen, flutamide (α-α-α-trifluoro-2-methyl-4′-nitro-m-propionotoluidide or SCH 13521), suppresses the… 
Highly Cited
1966
Highly Cited
1966
Fluorescent treponemal antibody-absorption (FTA-ABS) test for syphilis.
The development of the fluorescent treponemal antibody-absorption (FTA-ABS) test 1 has been the result of continued attempts to… 
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