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Androgen Receptor Antagonists [MoA]

Known as: Androgen Receptor Antagonists, Androgen Receptor Inhibitor 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2016
024619982016

Related topics

Related topics

6 relations
Androgen Receptor AntagonistsFlutamidebicalutamidebicalutamide 50 MG Oral Tablet
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Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
Androgen Receptor Antagonists [MoA]
Flutamide
bicalutamide
enzalutamide
nilutamide
Androgen Receptor Antagonists

Papers overview

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2012
2012
In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer.
Previously available androgen receptor (AR) antagonists (bicalutamide, flutamide, and nilutamide) have limited activity against… (More)
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2012
2012
Design, synthesis, and biological evaluation of 4-phenylpyrrole derivatives as novel androgen receptor antagonists.
A series of 4-phenylpyrrole derivatives D were designed, synthesized, and evaluated for their potential as novel orally available… (More)
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2012
2012
The Three Dimensional Quantitative Structure Activity Relationships (3D-QSAR) and Docking Studies of Curcumin Derivatives as Androgen Receptor Antagonists
Androgen receptor antagonists have been proved to be effective anti-prostate cancer agents. 3D-QSAR and Molecular docking methods… (More)
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2011
2011
Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads.
The studies presented in this manuscript focus on characterization of transcriptomic responses to anti-androgens in zebrafish… (More)
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2011
2011
Discovery of aryloxy tetramethylcyclobutanes as novel androgen receptor antagonists.
An aryloxy tetramethylcyclobutane was identified as a novel template for androgen receptor (AR) antagonists via cell-based high… (More)
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2010
2010
The promise of novel androgen receptor antagonists.
 
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2009
2009
Development of androgen receptor antagonists with promising activity in castration-resistant prostate cancer.
Androgen receptor (AR) continues to play a central role in prostate cancers that relapse after androgen deprivation therapy, but… (More)
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2007
2007
2-(2,2,2-Trifluoroethyl)-5,6-dichlorobenzimidazole derivatives as potent androgen receptor antagonists.
The synthesis and in vivo SAR of N-benzyl, N-aceto, and N-ethylene ether derivatives of 2-(2,2,2-trifluoroethyl)-5,6-dichloro… (More)
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2005
2005
Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists.
A novel series of isoindoledione based compounds were identified as potent antagonists of the androgen receptor (AR). Co… (More)
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2002
2002
Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents.
A number of curcumin analogues were prepared and evaluated as potential androgen receptor antagonists against two human prostate… (More)
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