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Androgen Antagonists
Known as:
Antagonists, Androgen
, androgen inhibitor
, Anti-Androgen Agents
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A substance that prevents cells from making or using androgens (hormones that play a role in the formation of male sex characteristics…
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National Institutes of Health
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Related topics
Related topics
23 relations
Androgens
Estrogens
Finasteride
In Blood
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Narrower (13)
Chlormadinone Acetate
Cyproterone
Cyproterone Acetate
Flutamide
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Broader (2)
Hormone Antagonists
Pharmaceutical Preparations
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
C. Tran
,
Samedy Ouk
,
+16 authors
C. Sawyers
Science
2009
Corpus ID: 31981682
A Second Act for Antiandrogens Men with advanced prostate cancer are often treated with antiandrogens; drugs that inhibit the…
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Highly Cited
2004
Highly Cited
2004
Molecular determinants of resistance to antiandrogen therapy
C. Chen
,
D. Welsbie
,
+5 authors
C. Sawyers
Nature Network Boston
2004
Corpus ID: 1182764
Using microarray-based profiling of isogenic prostate cancer xenograft models, we found that a modest increase in androgen…
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Review
2004
Review
2004
Androgen receptor in prostate cancer.
C. Heinlein
,
Chawnshang Chang
Endocrine reviews
2004
Corpus ID: 24665772
The normal development and maintenance of the prostate is dependent on androgen acting through the androgen receptor (AR). AR…
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Review
2001
Review
2001
The development of androgen-independent prostate cancer
B. Feldman
,
D. Feldman
Nature Reviews. Cancer
2001
Corpus ID: 205020623
The normal prostate and early-stage prostate cancers depend on androgens for growth and survival, and androgen ablation therapy…
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Highly Cited
1999
Highly Cited
1999
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
N. Craft
,
Y. Shostak
,
M. Carey
,
C. Sawyers
Nature Network Boston
1999
Corpus ID: 29872918
Prostate cancer progresses from a hormone-sensitive, androgen-dependent stage to a hormone-refractory, androgen-independent tumor…
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Highly Cited
1998
Highly Cited
1998
Several environmental oestrogens are also anti-androgens.
P. Sohoni
,
J. Sumpter
Journal of Endocrinology
1998
Corpus ID: 18448967
There is presently considerable interest in endocrine disruption which is a new area of endocrinology concerned with chemicals…
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Review
1998
Review
1998
An updated review of environmental estrogen and androgen mimics and antagonists
C. Sonnenschein
,
A. Soto
Journal of Steroid Biochemistry and Molecular…
1998
Corpus ID: 16158451
Review
1991
Review
1991
Prostate specific antigen: a critical assessment of the most useful tumor marker for adenocarcinoma of the prostate.
J. E. Oesterling
Journal of Urology
1991
Corpus ID: 42259337
Highly Cited
1990
Highly Cited
1990
A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens.
J. Veldscholte
,
C. Ris-Stalpers
,
+7 authors
E. Mulder
Biochemical and Biophysical Research…
1990
Corpus ID: 27638114
Highly Cited
1989
Highly Cited
1989
A controlled trial of leuprolide with and without flutamide in prostatic carcinoma.
E. Crawford
,
M. Eisenberger
,
+6 authors
P. Goodman
New England Journal of Medicine
1989
Corpus ID: 46227977
To test the hypothesis that maximal androgen blockade improves the effectiveness of the treatment of prostatic cancer, we…
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