Androgen Antagonists

Known as: Antagonists, Androgen, androgen inhibitor, Anti-Androgen Agents 
A substance that prevents cells from making or using androgens (hormones that play a role in the formation of male sex characteristics… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Persistent androgen receptor (AR) transcriptional activity underlies resistance to AR-targeted therapy and progression to lethal… (More)
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Highly Cited
2010
Highly Cited
2010
Androgen receptor (AR) splice variants lacking the ligand binding domain (ARVs), originally isolated from prostate cancer cell… (More)
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Highly Cited
2009
Highly Cited
2009
The androgen receptor (AR) plays a key role in progression to incurable androgen ablation-resistant prostate cancer (PCA). We… (More)
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Review
2004
Review
2004
The normal development and maintenance of the prostate is dependent on androgen acting through the androgen receptor (AR). AR… (More)
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Highly Cited
2004
Highly Cited
2004
Using microarray-based profiling of isogenic prostate cancer xenograft models, we found that a modest increase in androgen… (More)
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Review
2001
Review
2001
The normal prostate and early-stage prostate cancers depend on androgens for growth and survival, and androgen ablation therapy… (More)
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Highly Cited
1999
Highly Cited
1999
Prostate cancer progresses from a hormone-sensitive, androgen-dependent stage to a hormone-refractory, androgen-independent tumor… (More)
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Highly Cited
1999
Highly Cited
1999
SummaryAdvanced prostate cancer is treated by androgen ablation and/or androgen receptor (AR) antagonists. In order to… (More)
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Highly Cited
1998
Highly Cited
1998
There is presently considerable interest in endocrine disruption which is a new area of endocrinology concerned with chemicals… (More)
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Highly Cited
1990
Highly Cited
1990
LNCaP prostate tumor cells contain an abnormal androgen receptor system. Progestagens, estradiol and anti-androgens can compete… (More)
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