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Androgen Antagonists

Known as: Antagonists, Androgen, androgen inhibitor, Anti-Androgen Agents 
A substance that prevents cells from making or using androgens (hormones that play a role in the formation of male sex characteristics… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
A Second Act for Antiandrogens Men with advanced prostate cancer are often treated with antiandrogens; drugs that inhibit the… Expand
Highly Cited
2004
Highly Cited
2004
Using microarray-based profiling of isogenic prostate cancer xenograft models, we found that a modest increase in androgen… Expand
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Review
2004
Review
2004
The normal development and maintenance of the prostate is dependent on androgen acting through the androgen receptor (AR). AR… Expand
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Review
2001
Review
2001
The normal prostate and early-stage prostate cancers depend on androgens for growth and survival, and androgen ablation therapy… Expand
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Highly Cited
1999
Highly Cited
1999
Prostate cancer progresses from a hormone-sensitive, androgen-dependent stage to a hormone-refractory, androgen-independent tumor… Expand
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Review
1998
Review
1998
For the last 40 y, substantial evidence has surfaced on the hormone-like effects of environmental chemicals such as pesticides… Expand
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Highly Cited
1998
Highly Cited
1998
There is presently considerable interest in endocrine disruption which is a new area of endocrinology concerned with chemicals… Expand
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Review
1991
Review
1991
PSA is a kallikrein-like, serine protease that is produced exclusively by the epithelial cells of all types of prostatic tissue… Expand
Highly Cited
1989
Highly Cited
1989
To test the hypothesis that maximal androgen blockade improves the effectiveness of the treatment of prostatic cancer, we… Expand
Highly Cited
1987
Highly Cited
1987
Prostate cancer is the most frequent malignancy in elderly men. Common presentations include asymptomatic prostate nodules… Expand