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Finasteride

Known as: (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, Finasterida, 4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5alpha,17beta)- 
A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver… 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Objective To update the "Testosterone Therapy in Men With Androgen Deficiency Syndromes" guideline published in 2010… 
Highly Cited
2005
Highly Cited
2005
Testosterone (T) therapy in older men with low serum T levels increases lean body mass and decreases fat mass. These changes… 
Highly Cited
2003
Highly Cited
2003
BACKGROUND Androgens are involved in the development of prostate cancer. Finasteride, an inhibitor of 5alpha-reductase, inhibits… 
Highly Cited
2003
Highly Cited
2003
BACKGROUND Benign prostatic hyperplasia is commonly treated with alpha-adrenergic-receptor antagonists (alpha-blockers) or 5alpha… 
Highly Cited
1998
Highly Cited
1998
Background Finasteride is known to improve urinary symptoms in men with benign prostatic hyperplasia, but the extent to which the… 
Highly Cited
1998
Highly Cited
1998
Contrary to common perceptions, the reliability of quantitative assays for the determination of drugs in biological fluids using… 
Review
1998
Review
1998
Highly Cited
1996
Highly Cited
1996
BACKGROUND Men with benign prostatic hyperplasia can be treated with alpha 1-adrenergic-antagonist drugs that relax prostatic… 
Highly Cited
1993
Highly Cited
1993
  • P. Walsh
  • The Journal of urology
  • 1993
  • Corpus ID: 13550733
Background Benign prostatic hyperplasia is a progressive, androgen-dependent disease resulting in enlargement of the prostate… 
Highly Cited
1992
Highly Cited
1992
The oral administration of finasteride, a 4-aza-steroid inhibitor of 5 alpha-reductase, decreases serum dihydrotestosterone…