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Finasteride

Known as: (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, Finasterida, 4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5alpha,17beta)- 
A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver… 
National Institutes of Health

Related topics

Related topics

32 relations

Broader (4)

5-alpha Reductase InhibitorsAntineoplastic AgentsEnzyme InhibitorsUrological Agents
AlopeciaAndrogen AntagonistsCYP3A7 protein, humanChild

Narrower (8)

CGP 53153Chibro-ProscarFinastidMK-906

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Frontal fibrosing alopecia: a multicenter review of 355 patients.
Highly Cited
2011
Highly Cited
2011
Comparison of dutasteride and finasteride for treating benign prostatic hyperplasia: the Enlarged Prostate International Comparator Study (EPICS)
Study Type – Therapy (RCT) 
Highly Cited
2006
Highly Cited
2006
Effect of finasteride on the sensitivity of PSA for detecting prostate cancer.
BACKGROUND In the Prostate Cancer Prevention Trial (PCPT), men receiving finasteride had a 24.8% lower risk of prostate cancer… 
Review
2006
Review
2006
A new look at the 5alpha-reductase inhibitor finasteride.
Finasteride is the first 5alpha-reductase inhibitor that received clinical approval for the treatment of human benign prostatic… 
Review
2003
Review
2003
The evaluation and management of hirsutism.
Highly Cited
1998
Highly Cited
1998
Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations.
Contrary to common perceptions, the reliability of quantitative assays for the determination of drugs in biological fluids using… 
Highly Cited
1998
Highly Cited
1998
The effect of finasteride on the risk of acute urinary retention and the need for surgical treatment among men with benign prostatic hyperplasia. Finasteride Long-Term Efficacy and Safety Study Group…
Highly Cited
1996
Highly Cited
1996
Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride.
When the human prostate cancer cell line, LNCaP 104-S, the growth of which is stimulated by physiological levels of androgen, is… 
Highly Cited
1992
Highly Cited
1992
The effect of finasteride in men with benign prostatic hyperplasia.
Background Benign prostatic hyperplasia is a progressive, androgen-dependent disease resulting in enlargement of the prostate… 
Highly Cited
1992
Highly Cited
1992
Finasteride, an inhibitor of 5 alpha-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia.
The oral administration of finasteride, a 4-aza-steroid inhibitor of 5 alpha-reductase, decreases serum dihydrotestosterone… 
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