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Finasteride

Known as: (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, Finasterida, 4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5alpha,17beta)- 
A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver… 
National Institutes of Health

Related topics

Related topics

32 relations

Broader (4)

5-alpha Reductase InhibitorsAntineoplastic AgentsEnzyme InhibitorsUrological Agents
AlopeciaAndrogen AntagonistsCYP3A7 protein, humanChild

Narrower (8)

CGP 53153Chibro-ProscarFinastidMK-906

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain
Review
2008
Review
2008
5alpha-reductase inhibitors in benign prostatic hyperplasia and prostate cancer risk reduction.
Review
2007
Review
2007
Social isolation stress and neuroactive steroids
Highly Cited
2007
Highly Cited
2007
Structural study of polymorphs and solvates of finasteride.
NMR and XRD data are reported for several new forms of finasteride, including the results of complete structure determinations… 
Review
2004
Review
2004
Does finasteride alter the pathology of the prostate and cancer grading?
All forms of androgen-deprivation therapy, including finasteride, induce distinctive histologic changes in benign and neoplastic… 
Highly Cited
2001
Highly Cited
2001
Combined effect of terazosin and finasteride on apoptosis, cell proliferation, and transforming growth factor‐β expression in benign prostatic hyperplasia
Medical treatment of benign prostatic hyperplasia (BPH) targets relief of symptoms by causing either relaxation of the prostatic… 
Highly Cited
2000
Highly Cited
2000
Anticonvulsive Effect of Swim Stress in Mice
Highly Cited
1999
Highly Cited
1999
Validity of short food frequency questionnaires used in cancer chemoprevention trials: results from the Prostate Cancer Prevention Trial.
Here, we describe the measurement characteristics of a 13-item dietary screener used in the Prostate Cancer Prevention Trial. We… 
Highly Cited
1995
Highly Cited
1995
Evidence for atrophy and apoptosis in the ventral prostate of rats given the 5 alpha-reductase inhibitor finasteride.
Castration causes cell loss in the rat ventral prostate through a process called apoptosis. Although 5 alpha-reductase inhibition… 
Highly Cited
1993
Highly Cited
1993
Benign prostatic hyperplasia in a transgenic mouse: a new hormonally sensitive investigatory model.
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