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5-alpha Reductase Inhibitors

Known as: 5-alpha-Reductase Inhibitors, Testosterone, Inhibitors, 5-alpha Reductase, Reductase Inhibitors, 5-alpha 
A substance that blocks an enzyme needed by the body to make dihydrotestosterone (a male sex hormone made from testosterone). Dihydrotestosterone can… 
National Institutes of Health

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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
PARP inhibitors for BRCA1/2-mutated and sporadic ovarian cancer: current practice and future directions
Poly(ADP-ribose) polymerase (PARP) inhibitors cause targeted tumour cell death in homologous recombination (HR)-deficient cancers… 
Review
2013
Review
2013
New β-Lactamase Inhibitors: a Therapeutic Renaissance in an MDR World
ABSTRACT As the incidence of Gram-negative bacterial infections for which few effective treatments remain increases, so does the… 
Review
2005
Review
2005
Recent developments in the design of specific Matrix Metalloproteinase inhibitors aided by structural and computational studies.
It has been 10 years since a 3-dimensional structure of the catalytic domain of a Matrix Metalloprotease (MMP) was revealed for… 
Review
2004
Review
2004
The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors.
Matrix metalloproteinases (MMPs) are a family of zinc-containing enzymes involved in the degradation and remodeling of… 
Highly Cited
2002
Highly Cited
2002
Aromatase inhibitors for male infertility.
Review
1996
Review
1996
Matrix metalloproteinases and their inhibition in periodontal treatment.
Matrix metalloproteinases (MMPs), produced by both infiltrating and resident cells of the periodontium, play a role in… 
Highly Cited
1993
Highly Cited
1993
Finasteride: a slow-binding 5 alpha-reductase inhibitor.
A microsomal preparation of human prostatic tissue was used to study the kinetics of interaction of steroid 5 alpha-reductase… 
Highly Cited
1992
Highly Cited
1992
Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.
Studies were performed to compare the effects of 5 alpha-reductase inhibition and antiandrogen receptor blockade on… 
Highly Cited
1990
Highly Cited
1990
Effects of finasteride (MK-906), a 5 alpha-reductase inhibitor, on circulating androgens in male volunteers.
Finasteride, a 5 alpha-reductase inhibitor, was administered to normal male volunteers in a blinded placebo-controlled study at… 
Highly Cited
1990
Highly Cited
1990
Aromatization mediates aggressive behavior in quail.
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