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  • Sarah M. Drawz, Christopher R. Bethel, +5 authors Robert A. Bonomo
  • Chemistry, Medicine
  • Biochemistry
  • 2009 (First Published: 2 June 2009)
  • Inhibitor-resistant class A beta-lactamases of the TEM and SHV families that arise by single amino acid substitutions are a significant threat to the efficacy of beta-lactam/beta-lactamase inhibitorContinue Reading
  • Sarah M. Drawz, Magdalena A. Taracila, Emilia Caselli, Fabio Prati, Robert A. Bonomo
  • Chemistry, Medicine
  • Protein science : a publication of the Protein…
  • 2011 (First Published: 1 June 2011)
  • In Pseudomonas aeruginosa, the chromosomally encoded class C cephalosporinase (AmpC β-lactamase) is often responsible for high-level resistance to β-lactam antibiotics. Despite years of study ofContinue Reading
  • James R Johnson, Brian D. Johnston, +9 authors Ritu Banerjee
  • Biology, Medicine
  • Journal of clinical microbiology
  • 2019 (First Published: 20 February 2019)
  • Escherichia coli sequence type 1193 (ST1193) is an emerging multidrug-resistant pathogen. We performed longitudinal and cross-sectional surveillance for ST1193 among clinical and fecal E. coliContinue Reading
  • Hector Mesa, Sarah M. Drawz, Richard Dykoski, Juan Carlos Manivel
  • Medicine
  • Histopathology
  • 2015 (First Published: 1 October 2015)
  • AIMS An increased amount of submucosal (SM) fat in the colon on imaging is considered to be characteristic of inflammatory bowel disease (IBD); however, a recent study in patients without IBDContinue Reading
  • Germán Bou, Elena Santillana, +11 authors John D. Buynak
  • Chemistry, Medicine
  • Journal of the American Chemical Society
  • 2010 (First Published: 29 September 2010)
  • Class D β-lactamases represent a growing and diverse class of penicillin-inactivating enzymes that are usually resistant to commercial β-lactamase inhibitors. As many such enzymes are found inContinue Reading