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Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects.
TLDR
Although great variability was found in both the amount of cortisol secreted and the time spent in secretory activity/hr, the secretory rate was quite constant at approximately .05 mg/min. Expand
Disrupted 24-hour patterns of cortisol secretion in psychotic depression.
TLDR
The data suggest an abnormal disinhibition during depressive illness of the neuroendocrine centers regulating adrenocorticotrophic hormone release, which may be involved in the hypersecretion of cortisol in certain depressed patients. Expand
ACTH and cortisol secretory patterns in man.
TLDR
It was concluded that any sampling period longer than 5 min gives an erroneous depiction of events and this was exemplified in the case of ACTH secretion. Expand
Mild Hypogonadotropic hypogonadism in obese men.
TLDR
A state of mild hypog onadotropic hypogonadism appears to be characteristic of obese men, which probably results from partial suppression of the pituitary by the elevated plasma estrogen levels the authors and others find in these men. Expand
Determination of plasma dexamethasone in the mother and the newborn after administration of the hormone in a clinical trial.
TLDR
Because 11-dehydrodexamethasone was not present in significant amounts in the neonate, it was concluded that other factors in addition to the conversion of dexameth asone to its 11 dehydro metabolite were responsible for the rapid clearance of DexamethAsone from fetal and neonatal circulation. Expand
Cortisol is secreted episodically by normal man.
TLDR
It was shown that in the early morning hours during sleep cortisol was secreted in episodic bursts which were separated by intervals during which there was no cortisol sec... Expand
24-Hour secretory pattern of dehydroisoandrosterone and dehydroisoandrosterone sulfate.
TLDR
In this patient, continuous secretion of cortisol by the tumor apparently abolished stimulation of the contralateral adrenal, and DHA production was negligible, and dehydroisoandrosterone sulfate analysis in plasma displayed a pattern which showed less synchronicity with DHA and cortisol and less fluctuation than did the free hormones. Expand
Cortisol secretion and metabolism in anorexia nervosa.
TLDR
Thyroid-function studies showed normal total and free thyroxine and thyrotropin, but low plasma tri-iodothyronine levels, but high plasma cortisol levels, which also appear in hypothyroid patients. Expand
Dehydroisoandrosterone is secreted episodically and synchronously with cortisol by normal man.
TLDR
In 4 studies in a normal man it was demonstrated that dehydroisoandrosterone (DHA) was secreted episodically and synchronously with cortisol, and a high degree of biological activity can be implied for DHA. Expand
Cortisol production in obesity.
TLDR
It is concluded that there is no functionally significant elevation of cortisol production in obese men or women: the increase in absolute production is solely a consequence of greaterLean body mass, and the production/U lean body mass is weight-invariant. Expand
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