Factor XII

Known as: Beta-Factor XIIa Part 1, Beta-Factor XIIa Part 2, Hageman factor 
Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1955-2018
0204019552017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Deep vein thrombosis (DVT) is a major cause of cardiovascular death. The sequence of events that promote DVT remains obscure… (More)
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Highly Cited
2011
Highly Cited
2011
The release of histones from dying cells is associated with microvascular thrombosis and, because histones activate platelets… (More)
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Highly Cited
2010
Highly Cited
2010
Mice lacking factor XII (fXII) or factor XI (fXI) are resistant to experimentally-induced thrombosis, suggesting fXIIa activation… (More)
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Highly Cited
2006
Highly Cited
2006
Formation of fibrin is critical for limiting blood loss at a site of blood vessel injury (hemostasis), but may also contribute to… (More)
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2006
2006
Contact activation of blood factor XII (FXII, Hageman factor) in neat-buffer solution is shown not to be specific for anionic… (More)
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Highly Cited
2005
Highly Cited
2005
Blood coagulation is thought to be initiated by plasma protease factor VIIa in complex with the membrane protein tissue factor… (More)
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1989
1989
Activation of the Hageman factor-kallikrein-kinin system by serratial 56-kDa proteinase was previously demonstrated (Matsumoto, K… (More)
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Highly Cited
1978
Highly Cited
1978
The mechanism by which negatively charged substances such as celite, kaolin, or ellagic acid contribute to the surface-dependent… (More)
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Highly Cited
1977
Highly Cited
1977
Human blood coagulation Factor XI was purified in 20% yield from plasma by ion exchange chromatography. The specific clotting… (More)
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Highly Cited
1973
Highly Cited
1973
The activation of Hageman factor in solid and fluid phase has been analyzed. Activation of highly purified Hageman factor… (More)
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