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Factor XII

Known as: Beta-Factor XIIa Part 1, Beta-Factor XIIa Part 2, Hageman factor 
Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the… 
National Institutes of Health

Related topics

Related topics

31 relations
Activated Partial Thromboplastin Time measurementBlood coagulationCoagulantsCoagulation factor XII Ag:ACnc:Pt:PPP:Qn:IA

Broader (3)

Blood Coagulation FactorSerine EndopeptidasesSerine Proteases

Narrower (3)

Factor XIIafactor XII Bernfactor XII Locarno

Papers overview

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Highly Cited
2011
Highly Cited
2011
Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo.
Highly Cited
2011
Highly Cited
2011
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding.
Recent studies indicate that the plasma contact system plays an important role in thrombosis, despite being dispensable for… 
Highly Cited
2002
Highly Cited
2002
Factor XII interacts with the multiprotein assembly of urokinase plasminogen activator receptor, gC1qR, and cytokeratin 1 on endothelial cell membranes.
Investigations were performed to define the factor XII (FXII) binding site(s) on cultured endothelial cells (HUVECs). Biotin- or… 
Highly Cited
1981
Highly Cited
1981
Activation of the classical pathway of complement by Hageman factor fragment
A fragment of activated Hageman factor (HFf) has been demonstrated to activate the classical pathway of complement in a manner… 
Highly Cited
1980
Highly Cited
1980
Autoactivation of human Hageman factor. Demonstration utilizing a synthetic substrate.
The kallikrein substrate H-D-Pro-Phe-Arg-p-nitroanilide was used in a direct spectrophotometric assay for activated Hageman… 
Highly Cited
1978
Highly Cited
1978
Role of surface in surface-dependent activation of Hageman factor (blood coagulation factor XII).
The mechanism by which negatively charged substances such as celite, kaolin, or ellagic acid contribute to the surface-dependent… 
Highly Cited
1977
Highly Cited
1977
Hageman factor substrates. Human plasma prekallikrein: mechanism of activation by Hageman factor and participation in hageman factor-dependent fibrinolysis.
Highly Cited
1973
Highly Cited
1973
ACTIVATION OF HAGEMAN FACTOR IN SOLID AND FLUID PHASES
The activation of Hageman factor in solid and fluid phase has been analyzed. Activation of highly purified Hageman factor… 
Highly Cited
1971
Highly Cited
1971
A PREALBUMIN ACTIVATOR OF PREKALLIKREIN
Activation of a plasma fraction containing unactivated Hageman factor and prekallikrein followed by chromatography of this… 
Highly Cited
1961
Highly Cited
1961
Studies on the action of Hageman factor: evidence that activated Hageman factor in turn activates plasma thromboplastin antecedent.
Hageman factor is a component of normal plasma which participates in the early stages of blood coagulation (1). In freshly drawn… 
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