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Factor XIIa

Known as: XIIa, Coagulation Factor, Factor XIIa [Chemical/Ingredient], Coagulation Factor XIIa 
Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, kallikrein (with cofactor HIGH MOLECULAR WEIGHT… 
National Institutes of Health

Related topics

Related topics

10 relations
CoagulantsProcess of secretionagonistsantagonists & inhibitors

Broader (1)

Factor XII

Narrower (1)

Hageman-Factor Fragments

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Dextran-induced lowering of prekallikrein proactivator and prekallikrein in rat plasma.
The intravenous injection into rats of dextran (average MW 70,000) 10 mg/100 g caused marked hypotension after a delay of about 5… 
2000
2000
A monoclonal antibody raised against human beta-factor XIIa which also recognizes alpha-factor XIIa but not factor XII or complexes of factor XIIa with C1 esterase inhibitor.
A monoclonal antibody (mAb 2/215) against human beta-factor XIIa (beta-FXIIa), was shown by equilibrium binding studies to have a… 
Highly Cited
1995
Highly Cited
1995
Identification and Characterization of a Binding Site for Platelets in the Apple 3 Domain of Coagulation Factor XI (*)
Activated platelets expose a specific, reversible high affinity (K 10 nM) binding site (n 1500 sites/platelet) for factor XI that… 
1994
1994
Generation of [Ala1,Thr6]bradykinin in the plasma of a snake, the reticulated python.
Incubation of heat-denatured plasma from the reticulated python, Python reticulatus with trypsin generated bradykinin-like… 
1987
1987
An Animal Model for the Detection of Hypotensive Side Effects of Immunoglobulin Preparations
Abstract. Intravenous administration of certain immunoglobulin preparations may cause severe adverse reactions, especially in… 
1982
1982
Hypotensive effects of plasma protein fraction. The relation between prekallikrein activator, bradykinin generation, and blood pressure in an animal model.
In a rat model, the relationship between the activity of PKA in human PPFs, the changes in arterial BK concentration, and the… 
1980
1980
Purification of guinea-pig plasma prekallikrein. Activation by prekallikrein activator derived from guinea-pig skin.
1980
1980
Kinetics of activation of prekallikrein by prekallikrein activator.
A 28 000 molecular weight activator of prekallikrein was isolated from human plasma, and the kinetics of its enzymic activity… 
1979
1979
The assay of prekallikrein activator in human blood products.
An assay for the determination of prekallikrein activator (PKA) in human blood products is described. Kallikrein released from a… 
Review
1978
Review
1978
The “Hageman” connection: Interrelationships of blood coagulation, fibrino(geno)lysis, kinin generation, and complement activation
The activation pathways for the generation of enzymes involved in blood clotting, clot lysis, complement activation, and kinin… 
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