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FSCN1 protein, human

Known as: fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus), human, 55 kDa Actin-Bundling Protein, fascin-1 protein, human 
Fascin (493 aa, ~55 kDa) is encoded by the human FSCN1 gene. This protein is involved in the formation of actin filaments.
National Institutes of Health

Related topics

Related topics

16 relations
Actin-Binding ProteinCell MovementCell ProliferationCytokinesis

Broader (3)

Carrier ProteinsFascinMicrofilament Proteins

Papers overview

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Highly Cited
2011
Highly Cited
2011
Micro‐RNA signature of the epithelial–mesenchymal transition in endometrial carcinosarcoma
Endometrial carcinosarcomas (ECSs) undergo a true epithelial‐mesenchymal transition (EMT). The molecular determinants of the EMT… 
Highly Cited
2010
Highly Cited
2010
Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis
The high resolution structure of the cytoskeleton in dendritic spines and their precursors, dendritic filopodia, was… 
Highly Cited
2010
Highly Cited
2010
miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness
Micro RNAs are small non-coding RNAs, which regulate fundamental cellular and developmental processes at the transcriptional and… 
Highly Cited
2003
Highly Cited
2003
Formation of filopodia-like bundles in vitro from a dendritic network
We report the development and characterization of an in vitro system for the formation of filopodia-like bundles. Beads coated… 
Highly Cited
2003
Highly Cited
2003
Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro.
Highly Cited
2000
Highly Cited
2000
Multiple-particle tracking measurements of heterogeneities in solutions of actin filaments and actin bundles.
Highly Cited
1997
Highly Cited
1997
Identification of an Actin Binding Region and a Protein Kinase C Phosphorylation Site on Human Fascin*
Fascin is a 55-58-kDa actin-bundling protein, the actin binding of which is regulated by phosphorylation (Yamakita, Y., Ono, S… 
Highly Cited
1996
Highly Cited
1996
beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex
Catenins were first characterized as linking the cytoplasmic domains of cadherin cell-cell adhesion molecules to the cortical… 
Highly Cited
1994
Highly Cited
1994
Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension
Drosophila singed mutants were named for their gnarled bristle phenotype but severe alleles are also female sterile. Recently… 
Highly Cited
1979
Highly Cited
1979
Formation of filopodia in coelomocytes: Localization of Fascin, a 58,000 Dalton actin cross-linking protein
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