miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness

Abstract

Micro RNAs are small non-coding RNAs, which regulate fundamental cellular and developmental processes at the transcriptional and translational level. In breast cancer, miR-145 expression is downregulated compared with healthy control tissue. As several predicted targets of miR-145 potentially regulate cell motility, we aimed at investigating a potential… (More)
DOI: 10.1038/onc.2010.386

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@article{Gtte2010miR145dependentTO, title={miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness}, author={Martin G{\"{o}tte and Chuck Mohr and C-Y Koo and Cameron T Stock and A-K Vaske and Manuela Viola and Susan A. Ibrahim and Sirisha Peddibhotla and Yvonne H-F Teng and J Low and Klaus Ebnet and Ludwig Kiesel and George W. Yip}, journal={Oncogene}, year={2010}, volume={29}, pages={6569-6580} }