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FOXO3 gene

Known as: FKHR-LIKE 1, FORKHEAD BOX O3A, FOXO3A 
This gene is involved in transcriptional regulation and apoptosis.
National Institutes of Health

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7 relations
ApoptosisFOXO3 wt AlleleFOXO3A protein, humanHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Cell-to-Cell Variation in Gene Expression for Cultured Human Cells is Controlled in Trans by Diverse Genes: Implications for the Pathobiology of Aging.
Cell-to-cell variation in gene expression increases among homologous cells within multiple tissues during aging. We call this… 
2016
2016
Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner
ABSTRACT One major concern over the clinical application of embryonic stem cell (ESC)-derived cells is the potentiation of latent… 
2014
2014
Spontaneous presence of FOXO3-specific T cells in cancer patients
In the present study, we describe forkhead box O3 (FOXO3)-specific, cytotoxic CD8+ T cells existent among peripheral-blood… 
2014
2014
FOXO3A regulatory polymorphism and susceptibility to severe malaria in Gabonese children
The clinical course of malaria varies between affected individuals and host genetic factors have been shown to influence the… 
2011
2011
Cell-Penetrating TAT-FOXO3 Fusion Proteins Induce Apoptotic Cell Death in Leukemic Cells
FOXO proteins are Akt-regulated transcription factors involved in the control of cell cycle, DNA repair, stress defense… 
2009
2009
FoxO3a gene is a target of deletion in mouse lung adenocarcinoma.
Lung adenocarcinomas (LAC) of smokers and never-smokers differ from one another in epidemiology, and clinical and molecular… 
2006
2006
Induction of apoptosis by L-NMMA, via FKHRL1/ROCK pathway in human gastric cancer cells.
OBJECTIVE To investigate the apoptosis-inducing effect of endogenous nitric oxide (NO) suppression in gastric cancer cells and… 
2005
2005
Analysis of balanced rearrangements of chromosome 6 in acute leukemia : clustered breakpoints in q 22-q 23 and possible involvement of c-MYB in a new recurrent translocation
Recurrent chromosomal translocations are important diagnostic and prognostic markers contributing to the management of patients… 
Highly Cited
2004
Highly Cited
2004
Inhibition of phosphorylation of a forkhead transcription factor sensitizes human ovarian cancer cells to cisplatin.
The Forkhead family transcription factor FKHRL1 is an inducer of apoptosis in its unphosphorylated form and was recently reported… 
2002
2002
Insulin-Like Growth Factor-1 – Induced Phosphorylation of Transcription Factor FKHRL 1 Is Mediated by Phosphatidylinositol 3-Kinase / Akt Kinase and Role of This Pathway in Insulin-Like Growth Factor…
Insulin-like growth factor-1 (IGF-1) is a trophic factor promoting cell survival by activating phosphatidylinositol 3-kinase… 
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