FOXO3 gene

Known as: FKHR-LIKE 1, FORKHEAD BOX O3A, FOXO3A 
This gene is involved in transcriptional regulation and apoptosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
0102019972017

Papers overview

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Highly Cited
2009
Highly Cited
2009
FOXO1A and FOXO3A are two members of the FoxO family. FOXO3A has recently been linked to human longevity in Japanese, German and… (More)
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Highly Cited
2007
Highly Cited
2007
Erythroid cells accumulate hemoglobin as they mature and as a result are highly prone to oxidative damage. However, mechanisms of… (More)
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Highly Cited
2007
Highly Cited
2007
Forkhead transcription factors of the O class (FOXOs) are important targets of the phosphatidylinositol 3-kinase (PI3-kinase)/Akt… (More)
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Highly Cited
2007
Highly Cited
2007
Protein kinase-B (PKB) and its target, the forkhead transcription factor like 1 (FKHRL1)/FoxO3a, have been suggested as… (More)
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Highly Cited
2004
Highly Cited
2004
Members of the Foxo family, Foxo1 (Fkhr), Foxo3 (Fkhrl1), and Foxo4 (Afx), are mammalian homologs of daf-16, which influences… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Vascular endothelial growth factor (VEGF) is a potent angiogenic growth factor that promotes endothelial cell (EC… (More)
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Highly Cited
2004
Highly Cited
2004
Insulin-like growth factor-1 (IGF-1) and brain-derived neurotrophic factor (BDNF) are trophic factors required for the viability… (More)
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Highly Cited
2003
Highly Cited
2003
Developing sympathetic neurons die by apoptosis when deprived of NGF. BIM, a BH3-only member of the BCL-2 family, is induced… (More)
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Highly Cited
2002
Highly Cited
2002
Mutations in PTEN occur in 60-80% of prostate cancers and lead to a constitutive activation of the phosphatidylinositol 3-kinase… (More)
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Highly Cited
1998
Highly Cited
1998
Alveolar rhabdomyosarcomas are associated with unique chromosomal translocations t(2;13) and t(1;13), which arise from fusion of… (More)
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