FOXO3A protein, human

Known as: AF6q21 Protein, FKHRL1 protein, human, FOXO3 protein, human 
Forkhead box protein O3 (673 aa, ~71 kDa) is encoded by the human FOXO3 gene. This protein is involved in the modulation of transcription, apoptosis… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Breast cancer is the second leading cause of cancer death in women. Despite improvement in treatment over the past few decades… (More)
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Highly Cited
2009
Highly Cited
2009
Sirtuin 3 (SIRT3) is a member of the sirtuin family of proteins that promote longevity in many organisms. Increased expression of… (More)
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Highly Cited
2008
Highly Cited
2008
Human longevity is a complex phenotype with a significant familial component, yet little is known about its genetic antecedents… (More)
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Highly Cited
2007
Highly Cited
2007
Hematopoietic stem cells (HSCs) are maintained in an undifferentiated quiescent state within a bone marrow niche. Here we show… (More)
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Highly Cited
2006
Highly Cited
2006
Puma is an essential mediator of p53-dependent and -independent apoptosis in vivo. In response to genotoxic stress, Puma is… (More)
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Highly Cited
2004
Highly Cited
2004
Nuclear exclusion of the forkhead transcription factor FOXO3a by protein kinase Akt contributes to cell survival. We investigated… (More)
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Highly Cited
2003
Highly Cited
2003
Foxo transcription factors have been implicated in diverse biological processes, including metabolism, cellular stress responses… (More)
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Highly Cited
2002
Highly Cited
2002
Reactive oxygen species are required for cell proliferation but can also induce apoptosis. In proliferating cells this paradox is… (More)
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Highly Cited
2002
Highly Cited
2002
The signaling pathway from phosphoinositide 3-kinase to the protein kinase Akt controls organismal life-span in invertebrates and… (More)
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Highly Cited
2001
Highly Cited
2001
Serum- and glucocorticoid-inducible kinases (SGKs) form a novel family of serine/threonine kinases that are activated in response… (More)
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