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FOXO Family
Known as:
Fork Head Box Transcription Factor Class O
, Forkhead Box Transcription Factor Class O
, FoxO
A subfamily within the forkhead box (FOX) protein family, which is a family of transcription factors that contain a forkhead DNA-binding domain. FOXO…
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National Institutes of Health
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Related topics
Related topics
7 relations
FOXO1A protein, human
FOXO3A protein, human
Forkhead Box
Forkhead Box Protein O4
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
FoxO1 Haploinsufficiency Protects Against High-Fat Diet–Induced Insulin Resistance With Enhanced Peroxisome Proliferator–Activated Receptor γ Activation in Adipose Tissue
Jane J Kim
,
Pingping Li
,
Jessica Huntley
,
J. Chang
,
K. Arden
,
J. Olefsky
Diabetes
2009
Corpus ID: 18213695
OBJECTIVE Forkhead box O (FoxO) transcription factors represent evolutionarily conserved targets of insulin signaling, regulating…
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Review
2009
Review
2009
FoxO proteins: cunning concepts and considerations for the cardiovascular system.
K. Maiese
,
Zhao Zhong (兆忠) Chong (种)
,
Y. Shang
,
Jinling Hou
Clinical science
2009
Corpus ID: 20892998
Dysfunction in the cardiovascular system can lead to the progression of a number of disease entities that can involve cancer…
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Highly Cited
2009
Highly Cited
2009
Morphogenesis of Strongyloides stercoralis Infective Larvae Requires the DAF-16 Ortholog FKTF-1
Michelle L. Castelletto
,
H. C. Massey
,
J. Lok
PLoS Pathogens
2009
Corpus ID: 8170818
Based on metabolic and morphological similarities between infective third-stage larvae of parasitic nematodes and dauer larvae of…
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Review
2009
Review
2009
FOXO transcription factors: from cell fate decisions to regulation of human female reproduction.
J. Brosens
,
Miranda S C Wilson
,
E. Lam
Advances in Experimental Medicine and Biology
2009
Corpus ID: 24065878
All key reproductive events in the human ovary and uterus, including follicle activation, ovulation, implantation…
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Review
2008
Review
2008
FoxO transcription factors in oxidative stress response and ageing – a new fork on the way to longevity?
D. Sedding
Biological chemistry
2008
Corpus ID: 28085084
Abstract Forkhead box O (FoxO) transcription factors are important downstream targets of the PI3K/Akt signaling pathway and…
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Review
2007
Review
2007
Insulin resistance is an evolutionarily conserved physiological mechanism at the cellular level for protection against increased oxidative stress.
A. Erol
Bioessays
2007
Corpus ID: 22545018
Several protective cellular mechanisms protect against the accumulation of reactive oxygen species (ROS) and the concomitant…
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Highly Cited
2007
Highly Cited
2007
Epigallocatechin gallate (EGCG) mimics insulin action on the transcription factor FOXO1a and elicits cellular responses in the presence and absence of insulin.
Siobhan Anton
,
Laura Melville
,
G. Rena
Cellular Signalling
2007
Corpus ID: 34304925
Highly Cited
2006
Highly Cited
2006
RNA interference-mediated depletion of phosphoinositide 3-kinase activates forkhead box class O transcription factors and induces cell cycle arrest and apoptosis in breast carcinoma cells.
Shannon R Reagan-Shaw
,
N. Ahmad
Cancer Research
2006
Corpus ID: 37210678
Breast cancer is one of the most common malignancies affecting women in the Western world and one in seven women is predicted to…
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Review
2005
Review
2005
Transcriptional regulation of neuronal genes and its effect on neural functions: expression and function of forkhead transcription factors in neurons.
K. Fukunaga
,
T. Ishigami
,
T. Kawano
Journal of Pharmacological Sciences
2005
Corpus ID: 29429111
Forkhead box transcription factor, class O (FOXO) is a mammalian homologue of DAF-16, which is known to regulate the lifespan of…
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Highly Cited
2005
Highly Cited
2005
Aging and longevity: the IGF-1 enigma.
P. Anversa
Circulation Research
2005
Corpus ID: 16026468
See related article, pages 418–426 IGF-1 belongs to the insulin family of peptides and acts as a growth factor in many tissues…
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