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FOXO1A protein, human

Known as: Forkhead in Rhabdomyosarcoma, forkhead box O1 protein, human, forkhead box O1A (rhabdomyosarcoma) protein, human 
Forkhead box protein O1 (655 aa, ~70 kDa) is encoded by the human FOXO1 gene. This protein plays a role in the regulation of embryonic development… 
National Institutes of Health

Related topics

Related topics

14 relations
AKT Signaling PathwayAlveolar rhabdomyosarcomaAndrogen Receptor Regulation PathwayDNA-Binding Proteins

Broader (1)

Forkhead Box Protein O1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
FOXO1 and LXRα downregulate the apolipoprotein A-I gene expression during hydrogen peroxide-induced oxidative stress in HepG2 cells
Reactive oxygen species damage various cell components including DNA, proteins, and lipids, and these impairments could be a… 
2015
2015
FoxO1: mute for a tuned metabolism?
2014
2014
Preserved Energy Balance in Mice Lacking FoxO1 in Neurons of Nkx2.1 Lineage Reveals Functional Heterogeneity of FoxO1 Signaling Within the Hypothalamus
Transcription factor forkhead box O1 (FoxO1) regulates energy expenditure (EE), food intake, and hepatic glucose production… 
2013
2013
D 4476 , a cell-permeant inhibitor of CK 1 , suppresses the site-specific phosphorylationandnuclear exclusion of FOXO 1 a
The protein kinase CK1 phosphorylates serine residues that are located close to another phosphoserine in the consensus pSerXaa… 
Highly Cited
2010
Highly Cited
2010
FOXO1A is a target for HER2-overexpressing breast tumors.
Trastuzumab treatment has improved the overall survival of HER2-overexpressing breast cancer patients. However, many of these… 
Highly Cited
2007
Highly Cited
2007
Epigallocatechin gallate (EGCG) mimics insulin action on the transcription factor FOXO1a and elicits cellular responses in the presence and absence of insulin.
2007
2007
Constitutively active FOXO1a and a DNA-binding domain mutant exhibit distinct co-regulatory functions to enhance progesterone receptor A activity.
FOXO (Forkhead box O1 transcription factors) factors interact with and modify the activity of other transcription factors… 
Highly Cited
2006
Highly Cited
2006
RNA interference-mediated depletion of phosphoinositide 3-kinase activates forkhead box class O transcription factors and induces cell cycle arrest and apoptosis in breast carcinoma cells.
Breast cancer is one of the most common malignancies affecting women in the Western world and one in seven women is predicted to… 
2005
2005
FoxO1a-Cyclic GMP-Dependent Kinase I Interactions Orchestrate Myoblast Fusion
ABSTRACT The regulatory circuits that orchestrate mammalian myoblast cell fusion during myogenesis are poorly understood. The… 
Highly Cited
2004
Highly Cited
2004
FoxO1a can alter cell cycle progression by regulating the nuclear localization of p27kip in granulosa cells.
Forkhead transcription factors of the FOXO family are important downstream targets of the phosphatidylinositol 3-kinase pathway… 
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