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FHA Domain
Known as:
Forkhead-Associated Domain
The FHA (Forkhead-Associated) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for…
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National Institutes of Health
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Related topics
Related topics
4 relations
Afadin
CHEK2 protein, human
Ki-67 Antigen
NBS1 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions
Amber L. Couzens
,
J. D. Knight
,
+10 authors
A. Gingras
Science Signaling
2013
Corpus ID: 206672249
Phosphoprotein recognition directs kinase-phosphatase interactions at multiple levels in the mammalian Hippo pathway. Switching…
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Highly Cited
2009
Highly Cited
2009
Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair
R. S. Williams
,
Gerald E. Dodson
,
+8 authors
J. Tainer
Cell
2009
Corpus ID: 16538489
Highly Cited
2008
Highly Cited
2008
Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin
C. Spycher
,
E. Miller
,
+5 authors
M. Stucki
Journal of Cell Biology
2008
Corpus ID: 6105956
The MRE11–RAD50–Nijmegen breakage syndrome 1 (NBS1 [MRN]) complex accumulates at sites of DNA double-strand breaks (DSBs) in…
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Highly Cited
2007
Highly Cited
2007
RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins
N. Mailand
,
S. Bekker-Jensen
,
+4 authors
J. Lukas
Cell
2007
Corpus ID: 14232192
Highly Cited
2007
Highly Cited
2007
RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly
M. Huen
,
R. Grant
,
+4 authors
Junjie Chen
Cell
2007
Corpus ID: 11496176
Highly Cited
2007
Highly Cited
2007
Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase
N. Kolas
,
J. R. Chapman
,
+10 authors
D. Durocher
Science
2007
Corpus ID: 22684375
Cells respond to DNA double-strand breaks by recruiting factors such as the DNA-damage mediator protein MDC1, the p53-binding…
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Review
2006
Review
2006
IκB kinase complexes: gateways to NF-κB activation and transcription
C. Scheidereit
Oncogene
2006
Corpus ID: 7017330
Transcription factors of the NF-κB family regulate hundreds of genes in the context of multiple important physiological and…
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Highly Cited
2004
Highly Cited
2004
Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1
Stephan Schawalder
,
M. Kabani
,
I. Howald
,
Urmila Choudhury
,
M. Werner
,
D. Shore
Nature
2004
Corpus ID: 4415766
Regulation of ribosome biogenesis is central to the control of cell growth. In rapidly growing yeast cells, ribosomal protein (RP…
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Highly Cited
2003
Highly Cited
2003
MDC1 is required for the intra-S-phase DNA damage checkpoint
M. Goldberg
,
M. Stucki
,
+5 authors
S. Jackson
Nature
2003
Corpus ID: 4301037
MRE11, RAD50 and NBS1 form a highly conserved protein complex (the MRE11 complex) that is involved in the detection, signalling…
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Highly Cited
1998
Highly Cited
1998
Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint.
Z. Sun
,
J. Hsiao
,
D. Fay
,
D. Stern
Science
1998
Corpus ID: 20593464
The Rad53 protein kinase of Saccharomyces cerevisiae is required for checkpoints that prevent cell division in cells with damaged…
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