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FHA Domain
Known as:
Forkhead-Associated Domain
The FHA (Forkhead-Associated) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for…
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National Institutes of Health
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Related topics
Related topics
4 relations
Afadin
CHEK2 protein, human
Ki-67 Antigen
NBS1 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Characterization of the APLF FHA–XRCC1 phosphopeptide interaction and its structural and functional implications
Kyungmin Kim
,
L. Pedersen
,
T. Kirby
,
E. DeRose
,
R. London
Nucleic Acids Research
2017
Corpus ID: 23413650
Abstract Aprataxin and PNKP-like factor (APLF) is a DNA repair factor containing a forkhead-associated (FHA) domain that supports…
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Review
2014
Review
2014
Protein interactome analysis of 12 mitogen‐activated protein kinase kinase kinase in rice using a yeast two‐hybrid system
Raksha Singh
,
Jae-eun Lee
,
+7 authors
Nam‐Soo Jwa
Proteomics
2014
Corpus ID: 7765160
The mitogen‐activated protein kinase (MAPK) cascade is composed at least of MAP3K (for MAPK kinase kinase), MAP2K, and MAPK…
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2012
2012
Structural Delineation of MDC 1-FHA Domain Binding with CHK 2-pThr 68
Hsin-Hui Wu
,
Pei-Yu Wu
,
Kai-Fa Huang
,
Y. Kao
,
M. Tsai
2012
Corpus ID: 42598768
Mammalian MDC1 interacts with CHK2 in the regulation of DNA damage-induced S-phase checkpoint and apoptosis, which is directed by…
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2011
2011
Characterization of the specific interaction between archaeal FHA domain-containing protein and the promoter of a flagellar-like gene-cluster and its regulation by phosphorylation.
Xin Duan
,
Zheng-Guo He
Biochemical and Biophysical Research…
2011
Corpus ID: 25836665
2008
2008
Location-specific functions of the two forkhead-associated domains in Rad53 checkpoint kinase signaling.
Angela Tam
,
B. Pike
,
J. Heierhorst
Biochemistry
2008
Corpus ID: 33880161
Signaling proteins often contain multiple modular protein-protein interaction domains of the same type. The Saccharomyces…
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2007
2007
Launching a ubiquitination cascade at DNA breaks
X. H. Yang
,
L. Zou
Proceedings of the National Academy of Sciences…
2007
Corpus ID: 2166050
The BRCA1 gene was cloned in 1994 as the first tumor suppressor of hereditary breast cancer, and it has been heavily studied ever…
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2006
2006
SUMO-binding Motifs Mediate the Rad60-dependent Response to Replicative Stress and Self-association*
G. Raffa
,
J. Wohlschlegel
,
J. Yates
,
M. N. Boddy
Journal of Biological Chemistry
2006
Corpus ID: 44400822
In fission yeast, the replication checkpoint is enforced by the kinase Cds1 (human Chk2), which regulates both cell cycle…
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2004
2004
Cds1 Phosphorylation by Rad3-Rad26 Kinase Is Mediated by Forkhead-associated Domain Interaction with Mrc1*
Katsunori Tanaka
,
P. Russell
Journal of Biological Chemistry
2004
Corpus ID: 30319232
The protein kinase Cds1 is an effector of the replication checkpoint in the fission yeast Schizosaccharomyces pombe. Cds1 is…
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2002
2002
Forkhead-associated Domains of the Tobacco NtFHA1 Transcription Activator and the Yeast Fhl1 Forkhead Transcription Factor Are Functionally Conserved*
Moonil Kim
,
Joon-Woo Ahn
,
K. Song
,
K. Paek
,
H. Pai
Journal of Biological Chemistry
2002
Corpus ID: 24980545
NtFHA1 encodes a novel protein containing the forkhead-associated (FHA) domain and the acidic domain in Nicotiana tabacum. NtFHA1…
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2000
2000
FHA domain boundaries of the Dun1p and Rad53p cell cycle checkpoint kinases
A. Hammet
,
B. Pike
,
+5 authors
J. Heierhorst
FEBS Letters
2000
Corpus ID: 33546736
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