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FBXO11 gene

Known as: PROTEIN ARGININE METHYLTRANSFERASE 9, ubiquitin protein ligase E3 component n-recognin 6, VIT1 
This gene plays a role in the recognition of proteins to be ubiquitinylated.
National Institutes of Health

Related topics

Related topics

5 relations
F-Box Only Protein 11F-Box ProteinsUbiquitinated Protein DegradationUbiquitination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
PRMT9 promotes hepatocellular carcinoma invasion and metastasis via activating PI3K/Akt/GSK‐3β/Snail signaling
Protein arginine methyltransferases (PRMT) catalyze protein arginine methylation and play an important role in many biological… 
Highly Cited
2015
Highly Cited
2015
PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145
The human genome encodes a family of nine protein arginine methyltransferases (PRMT1–9), whose members can catalyse three… 
Highly Cited
2015
Highly Cited
2015
FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development.
Highly Cited
2015
Highly Cited
2015
The Oncogenic MicroRNA-21 Inhibits the Tumor Suppressive Activity of FBXO11 to Promote Tumorigenesis*
Background: miR-21 is overexpressed in many human cancers. Results: FBXO11 (a member of the F-box subfamily lacking a distinct… 
Highly Cited
2012
Highly Cited
2012
FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas
BCL6 is the product of a proto-oncogene implicated in the pathogenesis of human B-cell lymphomas. By binding specific DNA… 
Highly Cited
2009
Highly Cited
2009
The Substrate Recognition Domains of the N-end Rule Pathway*
The N-end rule pathway is a ubiquitin-dependent system where E3 ligases called N-recognins, including UBR1 and UBR2, recognize… 
Highly Cited
2007
Highly Cited
2007
FBXO11 Promotes the Neddylation of p53 and Inhibits Its Transcriptional Activity*
The p53 tumor suppressor is regulated by post-translational modification, including ubiquitination, phosphorylation and… 
Review
2007
Review
2007
Protein Arginine Methyltransferases: from Unicellular Eukaryotes to Humans
Eukaryotic cells extend their polypeptide diversity beyond the constraints of the encoded amino acids by means of… 
Highly Cited
2006
Highly Cited
2006
A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse.
Otitis media (OM), inflammation of the middle ear, is the most common cause of hearing impairment and surgery in children… 
Highly Cited
2006
Highly Cited
2006
FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues.
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