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F-Box Proteins

Known as: F-Box Domain Protein, Domain Protein, F-Box, Protein Family, F-Box 
A family of proteins that share the F-BOX MOTIF and are involved in protein-protein interactions. They play an important role in process of protein… Expand
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (18)

ChtA protein, DictyosteliumEID1 protein, ArabidopsisEmi2 protein, mouseFBXL17 protein, human
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F-Box MotifsFBXL12 geneFBXL21 geneFBXL22 gene
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Papers overview

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Review
2013
Review
2013
Mechanisms and function of substrate recruitment by F-box proteins
S phase kinase-associated protein 1 (SKP1)–cullin 1 (CUL1)–F-box protein (SCF) ubiquitin ligase complexes use a family of F-box… Expand
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Highly Cited
2013
Highly Cited
2013
Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins
The modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box protein substrate receptors that… Expand
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Highly Cited
2009
Highly Cited
2009
SnapShot: F Box Proteins II
Ago Trh txn factor, trachea development CycE cyclin, cell cycle Cdk2dMyc txn factor, cell growth/proliferation Notch… Expand
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Highly Cited
2009
Highly Cited
2009
F-box-directed CRL complex assembly and regulation by the CSN and CAND1.
The COP9 signalosome (CSN) is thought to maintain the stability of cullin-RING ubiquitin ligases (CRL) by limiting the… Expand
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Highly Cited
2007
Highly Cited
2007
F-Box Proteins in Rice. Genome-Wide Analysis, Classification, Temporal and Spatial Gene Expression during Panicle and Seed Development, and Regulation by Light and Abiotic Stress1[W][OA]
F-box proteins constitute a large family in eukaryotes and are characterized by a conserved F-box motif (approximately 40 amino… Expand
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Highly Cited
2006
Highly Cited
2006
F-box-like domain in the polerovirus protein P0 is required for silencing suppressor function.
Plants employ small RNA-mediated posttranscriptional gene silencing as a virus defense mechanism. In response, plant viruses… Expand
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Highly Cited
2005
Highly Cited
2005
Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels
BackgroundSCF ubiquitin ligases target numerous proteins for ubiquitin dependent proteolysis, including p27 and cyclin E. SCF and… Expand
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Highly Cited
2003
Highly Cited
2003
Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo.
SCF ubiquitin ligases, composed of three major subunits, Skp1, Cul1, and one of many F box proteins (Fbps), control the… Expand
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Highly Cited
2001
Highly Cited
2001
Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses.
Destruction of beta-catenin is regulated through phosphorylation-dependent interactions with the F box protein beta-TrCP. A novel… Expand
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Review
2000
Review
2000
The F-box protein family
SummaryThe F-box is a protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction. F… Expand
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