• Publications
  • Influence
The endocrinology and developmental biology of the prostate.
I. Introduction MALE accessory sex glands such as the prostate, seminal vesicle, and bulbourethral gland have served in various capacities as models for investigating the action of androgens inExpand
  • 871
  • 32
Increased adipose tissue in male and female estrogen receptor-alpha knockout mice.
Estrogen regulates the amount of white adipose tissue (WAT) in females, but its role in males and whether WAT effects involve estrogen receptor-alpha (ERalpha) or ERbeta were unclear. We analyzed theExpand
  • 515
  • 27
Increased adipose tissue in male and female estrogen receptor-α knockout mice
Estrogen regulates the amount of white adipose tissue (WAT) in females, but its role in males and whether WAT effects involve estrogen receptor-α (ERα) or ERβ were unclear. We analyzed the role ofExpand
  • 958
  • 23
Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium.
Estradiol-17beta (E2) acts through the estrogen receptor (ER) to regulate uterine growth and functional differentiation. To determine whether E2 elicits epithelial mitogenesis through epithelial ERExpand
  • 503
  • 17
Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse.
Male rats made hypothyroid during neonatal life show unprecedented increases in adult testis size and daily sperm production (DSP). To determine if this effect was unique to the rat or could also beExpand
  • 169
  • 14
The soy isoflavone genistein decreases adipose deposition in mice.
Adipose tissue is responsive to estrogen and expresses both estrogen receptor alpha and beta. To test the hypothesis that the estrogenic soy isoflavone genistein can have effects on adipose tissue,Expand
  • 257
  • 13
The Antiproliferative Action of Progesterone in Uterine Epithelium Is Mediated by Hand2
A progesterone-regulated transcription factor regulates stromal-epithelial communication in early pregnancy. During pregnancy, progesterone inhibits the growth-promoting actions of estrogen in theExpand
  • 237
  • 13
Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17alpha-ethinyl oestradiol.
Approximately 2 million women in the USA and Europe continue taking oral contraceptives each year during undetected pregnancy due primarily to non-compliance and also to individual variation inExpand
  • 114
  • 13
A Physiologically Based Approach To the Study of Bisphenol a and Other Estrogenic Chemicals On the Size of Reproductive Organs, Daily Sperm Production, and Behavior
Two chemicals previously shown to have estrogenic activity, bisphenol A and octylphenol, were examined for their effects on accessory reproductive organs and daily sperm production in male offspringExpand
  • 738
  • 12
Role of Estrogens in Adipocyte Development and Function
Estrogen has historically been viewed as a major regulator of adipose tissue in adult females, but recent work has indicated that estrogen's role in adipose biology may be broader than initiallyExpand
  • 323
  • 12