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FANFT

Known as: Formamide, N-(4-(5-nitro-2-furanyl)-2-thiazolyl)-, FANFT [Chemical/Ingredient], formamidonitrofurylthiazole 
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
National Institutes of Health

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ANFT

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Thiazoles
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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1991
1991
Synthesis and in vivo photodynamic activity of some bacteriochlorin derivatives against bladder tumors in rodents.
Bacteriochlorins have been suggested as potential photosensitizers for use in photodynamic therapy. We have shown that… 
Highly Cited
1986
Highly Cited
1986
Photodynamic treatment of transplantable bladder tumors in rodents after pretreatment with chloroaluminum tetrasulfophthalocyanine.
1985
1985
Multi-stage carcinogenesis in the urinary bladder.
1984
1984
Tumor production in germ-free rats fed 5-nitrofurans.
Highly Cited
1981
Highly Cited
1981
Effect of L-tryptophan and sodium saccharin on urinary tract carcinogenesis initiated by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
The effect of sodium saccharin (SAC) or L-tryptophan (LT) on urinary bladder carcinogenesis initiated by feeding N-[4-(5-nitro-2… 
Highly Cited
1981
Highly Cited
1981
Aspirin inhibition of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced lesions of the urinary bladder correlated with inhibition of metabolism by bladder prostaglandin endoperoxide synthetase.
The effects of aspirin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT) -induced urinary bladder lesions, endogenous… 
Highly Cited
1979
Highly Cited
1979
Radiation Therapy and cis-diammine-dichloroplatinum (II) in transplantable and primary murine bladder cancer.
1979
1979
Action of nitrofurans on E. coli: mutation and induction and repair of daughter-strand gaps in DNA.
1976
1976
Mutagenic activity of carcinogenic and noncarcinogenic nitrofurans and of urine of rats fed these compounds.
1974
1974
Chemotherapy of experimental transitional-cell carcinoma.
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