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FANFT

Known as: Formamide, N-(4-(5-nitro-2-furanyl)-2-thiazolyl)-, FANFT [Chemical/Ingredient], formamidonitrofurylthiazole 
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
National Institutes of Health

Papers overview

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2005
2005
SummaryExtracorporeal shock wave lithotripsy has become established worldwide as the method of choice for the treatment of… Expand
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Highly Cited
1992
Highly Cited
1992
Acrolein, a reactive, alpha,beta-unsaturated aldehyde which is ubiquitous in the environment, forms DNA adducts, is mutagenic… Expand
Highly Cited
1984
Highly Cited
1984
A theoretical model of two-stage carcinogenesis has been hypothesized. Variables that are modeled include the populations of… Expand
1980
1980
Based on reports of regression of superficial bladder tumors after urinary diversion, a study was designed to measure the effects… Expand
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Highly Cited
1979
Highly Cited
1979
The existence of at least two stages in bladder carcinogenesis was evaluated in male Fischer rats using N-[14-(5-nitro-2-furyl)-2… Expand
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Highly Cited
1979
Highly Cited
1979
A comparison of two rapid and inexpensive in vivo mammalian assays and the Ames Salmonella assay is presented for 61 agents… Expand
Highly Cited
1977
Highly Cited
1977
Summary Normal urinary bladder transitional epithelium (urothelium) contains a permeability barrier to water and solutes… Expand
Review
1977
Review
1977
Summary Transitional cell carcinomas induced in syngeneic mice by the carcinogen N -[4-(5-nitro-2-furyl)-2-thiazolyl]formamide… Expand
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Highly Cited
1977
Highly Cited
1977
Nitrofurazone, nitrofurantoin, furazolidone, furaltadone and N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide (FANFT) were toxic to… Expand
Highly Cited
1974
Highly Cited
1974
Summary 22 nitrofurans were tested for ability to induce revertants of E. coli WP2 and its uvrA - derivative from tryp - to tryp… Expand