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FANFT

Known as: Formamide, N-(4-(5-nitro-2-furanyl)-2-thiazolyl)-, FANFT [Chemical/Ingredient], formamidonitrofurylthiazole 
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
National Institutes of Health

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ANFT

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Thiazoles
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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1991
1991
Synthesis and in vivo photodynamic activity of some bacteriochlorin derivatives against bladder tumors in rodents.
Bacteriochlorins have been suggested as potential photosensitizers for use in photodynamic therapy. We have shown that… 
Highly Cited
1986
Highly Cited
1986
Photodynamic treatment of transplantable bladder tumors in rodents after pretreatment with chloroaluminum tetrasulfophthalocyanine.
1985
1985
Multi-stage carcinogenesis in the urinary bladder.
1984
1984
Tumor production in germ-free rats fed 5-nitrofurans.
Highly Cited
1981
Highly Cited
1981
Aspirin inhibition of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced lesions of the urinary bladder correlated with inhibition of metabolism by bladder prostaglandin endoperoxide synthetase.
The effects of aspirin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT) -induced urinary bladder lesions, endogenous… 
Highly Cited
1981
Highly Cited
1981
Effect of L-tryptophan and sodium saccharin on urinary tract carcinogenesis initiated by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
The effect of sodium saccharin (SAC) or L-tryptophan (LT) on urinary bladder carcinogenesis initiated by feeding N-[4-(5-nitro-2… 
1981
1981
Correlation between the half-wave reduction potentials of nitroheterocycles and their mutagenicity in Chinese hamster V79 spheroids.
  • P. Olive
  • Mutation research
  • 1981
  • Corpus ID: 7748633
1980
1980
Morphological effects of mitomycin C administered intravesically to normal mice and mice with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induce bladder neoplasms.
The intravesical administration of mitomycin C to normal and N-[4-(5-nitro-2-furyl)-2-thiozolyl]formamide-induced bladder tumor… 
1979
1979
Intercellular Junctions In Fanft‐Induced Carcinomas Of Rat Urinary Bladder In Tissue Culture: In Situ Thin‐Section, Freeze‐Fracture, And Scanning Electron Microscopy Studies
This paper describes a set of simple methods for comparative light and electron microscopy studies on tissue cultured tumour… 
1974
1974
Chemotherapy of experimental transitional-cell carcinoma.
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