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FANFT

Known as: Formamide, N-(4-(5-nitro-2-furanyl)-2-thiazolyl)-, FANFT [Chemical/Ingredient], formamidonitrofurylthiazole 
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
National Institutes of Health

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Thiazoles
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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1990
1990
Biological effects of shock waves
SummaryExtracorporeal shock wave lithotripsy has become established worldwide as the method of choice for the treatment of… 
Highly Cited
1986
Highly Cited
1986
Photodynamic treatment of transplantable bladder tumors in rodents after pretreatment with chloroaluminum tetrasulfophthalocyanine.
1985
1985
Multi-stage carcinogenesis in the urinary bladder.
1980
1980
Effects of urine and continued exposure to carcinogen on progression of early neoplastic urinary bladder lesions.
Based on reports of regression of superficial bladder tumors after urinary diversion, a study was designed to measure the effects… 
Highly Cited
1979
Highly Cited
1979
Promoting effect of saccharin and DL-tryptophan in urinary bladder carcinogenesis.
The existence of at least two stages in bladder carcinogenesis was evaluated in male Fischer rats using N-[14-(5-nitro-2-furyl)-2… 
Highly Cited
1979
Highly Cited
1979
Radiation Therapy and cis-diammine-dichloroplatinum (II) in transplantable and primary murine bladder cancer.
Highly Cited
1977
Highly Cited
1977
Cytotoxicity and DNA damage to mammalian cells by nitrofurans.
Highly Cited
1977
Highly Cited
1977
Malignant transformation of urinary bladder in humans and in N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-exposed Fischer rats: ultrastructure of the major components of the permeability barrier.
Summary Normal urinary bladder transitional epithelium (urothelium) contains a permeability barrier to water and solutes… 
Review
1977
Review
1977
Intravesical and systemic chemotherapy of murine bladder cancer.
Summary Transitional cell carcinomas induced in syngeneic mice by the carcinogen N -[4-(5-nitro-2-furyl)-2-thiazolyl]formamide… 
1976
1976
Mutagenic activity of carcinogenic and noncarcinogenic nitrofurans and of urine of rats fed these compounds.
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