Skip to search formSkip to main contentSkip to account menu

FANFT

Known as: Formamide, N-(4-(5-nitro-2-furanyl)-2-thiazolyl)-, FANFT [Chemical/Ingredient], formamidonitrofurylthiazole 
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (1)

ANFT

Broader (1)

Thiazoles
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis.
  • Claes AnderströmS. JohanssonL. Von Schultz
  • Acta pathologica, microbiologica, et immunologica…
  • 2009
  • Corpus ID: 9059450
The influence of 0.535% phenacetin in the diet or mechanical perforation of the renal pelvis and urinary bladder of male Sprague… 
1986
1986
Effect of sodium phenobarbital and sodium saccharin in AIN-76A diet on carcinogenesis initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and N,N-dibutylnitrosamine in male F344 rats.
Promoting activities of sodium phenobarbital (PB) and sodium saccharin (SS), incorporated in a semisynthetic diet (AIN-76A), on 2… 
1985
1985
Low susceptibility of analbuminemic rats to induction of bladder cancer by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
The susceptibility of analbuminemic rats (Nagase analbuminemic rats; NAR) to induction of bladder cancer by oral N-[4-(5-nitro-2… 
1984
1984
A murine model for bladder cancer.
Growth characteristics, survival time, and various other parameters such as chromosome studies and DNA synthesis were evaluated… 
1982
1982
Time- and concentration-dependent inhibition of the clonogenic growth of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced murine bladder tumor cell lines by cis-diamminedichloroplatinum(II).
The influence of the concentration and time of exposure to cis-diamminedichloroplatinum on the inhibition of the clonogenic… 
1980
1980
Metabolism of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide by prostaglandin endoperoxide synthetase.
Cooxidative metabolism of the urinary bladder carcinogen N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide (FANFT) was examined using… 
1980
1980
Effect of overloading pathways on toxicity.
Overloading of metabolic pathways results in a disproportionate relationship between the concentration of drug and/or metabolites… 
1978
1978
The effects of topical instillation of adriamycin in bladder tumors of rats fed with FANFT.
Topical bladder instillation of adriamycin was evaluated in FANET produced rat tumors produced by diets containing (N-[4-(5-Nitro… 
1978
1978
A bladder tumor model response to immunotherapy.
The author presented results of BCG and Corynebacterium parvum treatment of the transplantable mouse FANFT bladder tumor carried… 
1976
1976
Enhancing effect of allopurinol on the induction of bladder cancer in rats by n-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
The effects of allopurinol on the induction of bladder cancer by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide (FANFT), excretion…