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FANFT

Known as: Formamide, N-(4-(5-nitro-2-furanyl)-2-thiazolyl)-, FANFT [Chemical/Ingredient], formamidonitrofurylthiazole 
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
National Institutes of Health

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ANFT

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Thiazoles
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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2005
2005
Biological effects of shock waves
SummaryExtracorporeal shock wave lithotripsy has become established worldwide as the method of choice for the treatment of… Expand
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1994
1994
Prohibitin gene is overexpressed but not mutated in rat bladder carcinomas and cell lines.
Prohibitin was isolated as a candidate antiproliferating gene in rat liver cells, and it has been suggested as a tumor suppressor… Expand
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Highly Cited
1992
Highly Cited
1992
Acrolein initiates rat urinary bladder carcinogenesis.
Acrolein, a reactive, alpha,beta-unsaturated aldehyde which is ubiquitous in the environment, forms DNA adducts, is mutagenic… Expand
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1987
1987
A dose response analysis of purpurin derivatives used as photosensitizers for the photodynamic treatment of transplantable FANFT induced urothelial tumors.
Rats engrafted with transplantable N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide (FANFT) induced urothelial tumors were treated… Expand
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1984
1984
A general probabilistic model of carcinogenesis: analysis of experimental urinary bladder cancer.
A theoretical model of two-stage carcinogenesis has been hypothesized. Variables that are modeled include the populations of… Expand
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1981
1981
Effect of L-tryptophan and sodium saccharin on urinary tract carcinogenesis initiated by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
The effect of sodium saccharin (SAC) or L-tryptophan (LT) on urinary bladder carcinogenesis initiated by feeding N-[4-(5-nitro-2… Expand
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Highly Cited
1979
Highly Cited
1979
Promoting effect of saccharin and DL-tryptophan in urinary bladder carcinogenesis.
The existence of at least two stages in bladder carcinogenesis was evaluated in male Fischer rats using N-[14-(5-nitro-2-furyl)-2… Expand
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Highly Cited
1979
Highly Cited
1979
The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assays.
A comparison of two rapid and inexpensive in vivo mammalian assays and the Ames Salmonella assay is presented for 61 agents… Expand
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Review
1977
Review
1977
Intravesical and systemic chemotherapy of murine bladder cancer.
Summary Transitional cell carcinomas induced in syngeneic mice by the carcinogen N -[4-(5-nitro-2-furyl)-2-thiazolyl]formamide… Expand
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Highly Cited
1976
Highly Cited
1976
Early lesions in experimental bladder cancer: scanning electron microscopy of cell surface markers.
The administration of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide (FANFT) at a dose of 0.2% of the diet to male Fischer rats… Expand
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