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Why drinking green tea could prevent cancer
Epidemiological studies suggest that the consumption of green tea may help prevent cancers in humans; also, breast and prostate cancers in animal models are reduced by green, but not black, tea. HereExpand
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Lipoxygenases - A Challenging Problem in Enzyme Inhibition and Drug Development
Lipoxygenases (LOXs), cytochromes P450 (CYPs) and cyclooxygenases (COXs) catalyze peroxidation of unsaturated fatty acids. In humans they convert arachidonic acid into a variety of eicosanoids, whichExpand
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Structure of curcumin in complex with lipoxygenase and its significance in cancer.
Scientific research provides documented evidence that fatty acid metabolites have profound impact on carcinogenesis. Intervention into dioxygenase pathways might therefore effect development,Expand
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Synthetic curcuminoids modulate the arachidonic acid metabolism of human platelet 12-lipoxygenase and reduce sprout formation of human endothelial cells
Platelet 12-lipoxygenase (P-12-LOX) is overexpressed in different types of cancers, including prostate cancer, and the level of expression is correlated with the grade of this cancer. ArachidonicExpand
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Effects of tacrolimus on hyperlipidemia after successful renal transplantation: a Southeastern Organ Procurement Foundation multicenter clinical study.
BACKGROUND Tacrolimus has been shown to have a less adverse effect on the lipid profiles of transplant patients when the drug is started as induction therapy. In order to determine the effectExpand
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Curcumin inhibits lipoxygenase by binding to its central cavity: theoretical and X-ray evidence.
Many lipoxygenase inhibitors including curcumin are currently being studied for their anti-carcinogenic properties. Curcumin is a naturally occurring polyphenolic phytochemical isolated from theExpand
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Inhibition of bladder tumor growth by the green tea derivative epigallocatechin-3-gallate.
PURPOSE We evaluated the green tea derivative epigallocatechin-3-gallate (EGCG) as an intravesical agent for the prevention of transitional cell tumor implantation. MATERIALS AND METHODS In vitroExpand
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Transperineal photodynamic ablation of the canine prostate.
PURPOSE Experiments were undertaken to determine the effects of transperineal interstitial photodynamic therapy on the canine prostate. MATERIALS AND METHODS Mongrel dogs were injectedExpand
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Curcumin prevents intravesical tumor implantation of the MBT-2 tumor cell line in C3H mice.
PURPOSE The development of an effective nontoxic intravesical agent that may be used immediately after bladder tumor resection to prevent the implantation of tumor cells would be a significantExpand
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The McNeal prostate: a review.
Prostate anatomy has been the subject of controversy for 200 years. In the 19th and early 20th centuries, lobar anatomy was accepted. Beginning in 1968 and for the next 25 years, John E. McNealExpand
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