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FAAH gene
Known as:
FAAH
, FAAH-1
, FATTY ACID AMIDE HYDROLASE
National Institutes of Health
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Related topics
Related topics
3 relations
FA2H gene
fatty acid alpha-hydroxylase
fatty acid amide hydrolase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Multitarget fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti‐inflammatory drug‐dependent gastrointestinal damage
O. Sasso
,
M. Migliore
,
+6 authors
D. Piomelli
The FASEB Journal
2015
Corpus ID: 5971825
The ability of nonsteroidal anti‐inflammatory drugs (NSAIDs) to inhibit cyclooxygenase (Cox)‐1 and Cox‐2 underlies the…
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2014
2014
Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models
T. Grim
,
Sudeshna Ghosh
,
Ku‐Lung Hsu
,
B. Cravatt
,
S. Kinsey
,
A. Lichtman
Pharmacology, Biochemistry and Behavior
2014
Corpus ID: 24896189
2011
2011
Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors.
Darin J. Gustin
,
Zhihua Ma
,
+13 authors
F. Kayser
Bioorganic & Medicinal Chemistry Letters
2011
Corpus ID: 30440432
Review
2007
Review
2007
Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors.
S. Saario
,
J. Laitinen
Basic & Clinical Pharmacology & Toxicology
2007
Corpus ID: 46010855
The specific protein target of delta9-tetrahydrocannabinol (delta9-THC), the main active ingredient of Cannabis sativa L., was…
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Highly Cited
2006
Highly Cited
2006
Development of the first potent and specific inhibitors of endocannabinoid biosynthesis.
T. Bisogno
,
M. Cascio
,
+8 authors
V. Di Marzo
Biochimica et Biophysica Acta
2006
Corpus ID: 23720734
Highly Cited
2006
Highly Cited
2006
Fatty acid amide hydrolase inhibitors from virtual screening of the endocannabinoid system.
S. Saario
,
A. Poso
,
R. Juvonen
,
T. Järvinen
,
O. Salo-Ahen
Journal of Medicinal Chemistry
2006
Corpus ID: 29621659
The endocannabinoid system consists of two cannabinoid receptors (CB1 and CB2), endogenous ligands (endocannabinoids), and the…
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Highly Cited
2005
Highly Cited
2005
Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency…
D. Leung
,
Wu Du
,
+4 authors
D. Boger
Bioorganic & Medicinal Chemistry Letters
2005
Corpus ID: 16579166
Highly Cited
2004
Highly Cited
2004
A simple stopped assay for fatty acid amide hydrolase avoiding the use of a chloroform extraction phase.
L. Boldrup
,
S. Wilson
,
A. Barbier
,
C. Fowler
Journal of Biochemical and Biophysical Methods
2004
Corpus ID: 12026173
Highly Cited
1999
Highly Cited
1999
Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen.
Christopher J. Fowler
,
Ulrika Janson
,
+4 authors
G. Tiger
Archives of Biochemistry and Biophysics
1999
Corpus ID: 21405489
The endogenous cannabimimetic anandamide is hydrolyzed by a fatty acid amide hydrolase to yield arachidonic acid and ethanolamine…
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Highly Cited
1998
Highly Cited
1998
An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase.
M. Patricelli
,
J. E. Patterson
,
D. Boger
,
B. Cravatt
Bioorganic & Medicinal Chemistry Letters
1998
Corpus ID: 275083
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