Zhihua Ma

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BACKGROUND This meta-analysis investigated the association between functional COX-2 gene polymorphisms and the risk of oral cancer. METHODS Several electronic databases were searched for published studies using combinations of keywords related to COX-2 gene polymorphisms and oral cancer. After selection of relevant studies, following strict inclusion and(More)
Glucagon-like peptide-1 (GLP-1) reduces blood glucose and improves abnormal metabolism caused by hyperglycemia. The formation of thrombus, one of major consequences suffered from diabetes, can be inhibited by the treatment of Hirudin (HV). This study was aimed to develop a fusion peptide which combines functions of GLP-1 and HV to treat diabetes and its(More)
Glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) have a similar but complementary role in regulating blood glucose level. This study was aimed to develop a functional-complementary dual insulinotropic peptide which releases both GLP-1 and GIP in vivo, and to investigate its therapeutic effect on type 2 diabetes in mice. We firstly(More)
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