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F3 gene

Known as: CD142, TISSUE THROMBOPLASTIN, TISSUE FACTOR 
This gene is involved in the blood coagulation process by initiating blood coagulation cascades.
National Institutes of Health

Related topics

Related topics

5 relations
Blood coagulationLigand BindingThromboplastinTissue Factor

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F3 wt Allele

Papers overview

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Highly Cited
2003
Highly Cited
2003
Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes.
Blood microparticles (MPs) in sickle cell disease (SCD) are reportedly derived only from erythrocytes and platelets. Yet in SCD… 
Highly Cited
2002
Highly Cited
2002
Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation
Review
2001
Review
2001
Structure and Biology of Tissue Factor Pathway Inhibitor
Summary Human tissue factor pathway inhibitor (TFPI) is a modular protein comprised of three Kunitz type domains flanked by… 
Highly Cited
1998
Highly Cited
1998
Vascular endothelial groth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: Conversion of prothrombin to thrombin results in progelatininase a activation and…
Production of vascular endothelial growth factor (VEGF) by cancer cells at invasive and metastatic sites is an important aspect… 
Highly Cited
1997
Highly Cited
1997
Apoptotic vascular endothelial cells become procoagulant
Whereas unperturbed endothelial cells provide potent anticoagulant properties, exposure to inflammatory and atherogenic stimuli… 
Highly Cited
1997
Highly Cited
1997
Mice lacking factor VII develop normally but suffer fatal perinatal bleeding
Blood coagulation in vivo is initiated by factor VII (FVII) binding to its cellular receptor tissue factor (TF). FVII is the only… 
Review
1995
Review
1995
Regulation of the tissue factor gene
The tissue factor (TF) gene is expressed in a cell type‐specific manner in vivo. It is constitutively expressed by several… 
Highly Cited
1993
Highly Cited
1993
Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis.
Disseminated intravascular thrombosis is a frequent complication of endotoxic shock, and modulation of endothelial cell… 
Highly Cited
1991
Highly Cited
1991
Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites
Lipopolysaccharide (LPS) activation of cells of monocytic lineage leads to rapid and transient expression of a set of… 
Highly Cited
1987
Highly Cited
1987
Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro.
Endotoxemia is frequently associated clinically with disseminated intravascular coagulation (DIC); however, the mechanism of… 
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