F2RL3 gene

Known as: PROTEASE-ACTIVATED RECEPTOR 4, THROMBIN RECEPTOR-LIKE 3, F2R like thrombin/trypsin receptor 3 
This gene plays a role in both receptor signaling and platelet activation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
02420022018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Smoking accounts for a large share of lung cancer. F2RL3 methylation was recently identified as a biomarker closely reflecting… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
2015
2015
DNA hypomethylation in certain genes is associated with tobacco exposure but it is unknown whether these methylation changes… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
2014
2014
BACKGROUND Recent genome-wide DNA methylation studies have found a pronounced difference in methylation of the F2RL3 gene (also… (More)
  • table 1
  • table 3
Is this relevant?
2014
2014
BACKGROUND Smoking is a major cause of morbidity and mortality. Smoking-related epigenetic biomarkers may open new avenues to… (More)
Is this relevant?
Highly Cited
2013
Highly Cited
2013
A single cytosine-guanine dinucleotide (CpG) site within coagulation factor II (thrombin) receptor-like 3 (F2RL3) was recently… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2012
2012
AIMS In a recent genome-wide study, cytosine bases in the F2RL3 gene, which codes for a protein relevant for cardiovascular… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Tobacco smoking is responsible for substantial morbidity and mortality worldwide, in particular through cardiovascular, pulmonary… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2007
2007
Human lung fibroblasts express proteinase-activated receptor-1 (PAR1), PAR2 and PAR3, but not PAR4. Because PAR2 has inflammatory… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2004
2004
Active thrombin is found in the airways of patients with a variety of inflammatory lung diseases. However, whether thrombin… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
It is commonly accepted that thrombin exerts its proinflammatory properties through the activation of proteinase-activated… (More)
Is this relevant?