F2RL3 protein, human

Known as: coagulation factor II (thrombin) receptor-like 3 protein, human, Thrombin Receptor-Like 3, PAR-4 
Proteinase-activated receptor 4 (385 aa, ~41 kDa) is encoded by the human F2RL3 gene. This protein plays a role in both the mediation of receptor… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2018
0102019882018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Prostate apoptosis response-4 (Par-4) is a proapoptotic protein with intracellular functions in the cytoplasm and nucleus… (More)
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Highly Cited
2007
Highly Cited
2007
Deletion or mutation of the androgen receptor (AR) renders prostate tumors refractory to apoptosis by androgen ablation, the… (More)
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Highly Cited
2004
Highly Cited
2004
The LKB1 gene encodes a serine/threonine kinase that is mutated in the Peutz-Jeghers cancer syndrome. LKB1 is homologous to the… (More)
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Highly Cited
2003
Highly Cited
2003
The PAR-4 and PAR-1 kinases are necessary for the formation of the anterior–posterior (A–P) axis in Caenorhabditis elegans. PAR-1… (More)
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Highly Cited
2000
Highly Cited
2000
During the first cell cycle of Caenorhabditis elegans embryogenesis, asymmetries are established that are essential for… (More)
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Highly Cited
1999
Highly Cited
1999
The par genes are required to establish polarity in the Caenorhabditis elegans embryo. Mutations in two of these genes, par-3 and… (More)
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Highly Cited
1996
Highly Cited
1996
The par genes participate in the process of establishing cellular asymmetries during the first cell cycle of Caenorhabditis… (More)
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Highly Cited
1996
Highly Cited
1996
The atypical PKCs are involved in a number of important cellular functions, including cell proliferation. We report here that the… (More)
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Highly Cited
1996
Highly Cited
1996
The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of… (More)
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Highly Cited
1988
Highly Cited
1988
We have isolated and analyzed eight strict maternal effect mutations identifying four genes, par-1, par-2, par-3, and par-4… (More)
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