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F2RL3 wt Allele

Known as: Coagulation Factor II (Thrombin) Receptor-Like 3 wt Allele, PAR4 
Human F2RL3 wild-type allele is located in the vicinity of 19p12 and is approximately 3 kb in length. This allele, which encodes proteinase-activated… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

F2RL3 gene
G Protein-Coupled Receptor SignalingLigand BindingPlatelet ActivationReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
BINDING PROTEINS TO THE HUMAN THROMBIN RECEPTOR, PAR4
2016
2016
Development of a Series of (1-Benzyl-3-(6-methoxypyrimidin-3-yl)-5-(trifluoromethoxy)-1H-indol-2-yl)methanols as Selective Protease Activated Receptor 4 (PAR4) Antagonists with in Vivo Utility and…
Here, we describe the development of a series of highly selective PAR4 antagonists with nanomolar potency and selectivity versus… 
2016
2016
Differential anti-thrombotic benefit and bleeding risk profiles of antagonists of protease-activated receptor 1 and 4 in Cynomolgus Macaques.
2014
2014
Antithrombotic effects of PAR1 and PAR4 antagonists evaluated under flow and static conditions.
2014
2014
Erratum to Yeung et al. “12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity” (Thromb Haemost 2013; 110: 569–581)
2013
2013
Effects Of Biased PAR1 Ligands On Platelets and Endothelial Cells
Protease-activated receptor 1 (PAR1) is a widely expressed G protein coupled receptor (GPCR) that monitors the extracellular… 
2007
2007
PAR4 antagonists in inflammation
Slofstra and colleagues employ the Shwartzman model of LPS-induced inflammation in mice to show that inhibition of the thrombin… 
2006
2006
Inhibition of PAR4 signaling mediates ethanol-induced attenuation of platelet function in vitro.
BACKGROUND Reduction in coronary heart disease morbidity in response to moderate consumption of alcoholic beverages may be partly… 
2005
2005
Characterization of a novel protein from Proatheris superciliaris venom: proatherocytin, a 34-kDa platelet receptor PAR1 agonist.
2003
2003
[Mechanism of action of protease-activated receptors 1 and 4 in platelet activation].
This study was designed to compare the effects of protease-activated receptor 1 (PAR-1) and protease-activated receptor 4 (PAR-4… 
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