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F2R gene

Known as: CF2R, PAR-1, F2R 
This gene is involved in coagulation and proteolytic cleavage regulation.
National Institutes of Health

Related topics

Related topics

9 relations
F2R wt AlleleG Protein-Coupled Receptor SignalingLigand BindingProtease-Activated Receptor 1, human

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Activated protein C, protease activated receptor 1, and neuroprotection.
Protein C is a plasma serine protease zymogen whose active form, activated protein C (APC), exerts potent anticoagulant activity… 
Review
2012
Review
2012
Copper-catalyzed difluoromethylation of β,γ-unsaturated carboxylic acids: an efficient allylic difluoromethylation.
The difluoromethyl group (CF2H) is an intriguing structural motif, which has great potential for many applications in lifescience… 
2009
2009
Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels
Summary Thrombin-activated factor 2 receptor (F2R) links thrombosis to inflammation modulating interleukin (IL)6 synthesis. We… 
2007
2007
Active integration: new strategies for transgenesis
This paper presents novel methods for producing transgenic animals, with a further emphasis on how these techniques may someday… 
2007
2007
Retrospective Analysis of Coagulation Factor II Receptor (F2R) Sequence Variation and Coronary Heart Disease in Hypertensive Patients
Objectives—The purpose of this study was to evaluate the role of genetic variants within the coagulation factor II receptor (F2R… 
2004
2004
Par-1 regulates bicoid mRNA localisation by phosphorylating Exuperantia
The Ser/Thr kinase Par-1 is required for cell polarisation in diverse organisms such as yeast, worms, flies and mammals. During… 
2003
2003
Characterization of the Double-Partitioning Modules of R27: Correlating Plasmid Stability with Plasmid Localization
ABSTRACT Plasmid R27 contains two independent partitioning modules, designated Par1 and Par2, within transfer region 2. Par1 is… 
Highly Cited
2002
Highly Cited
2002
A Comparison of ALPHAScreen, TR-FRET, and TRF as Assay Methods for FXR Nuclear Receptors
New developments in detection technologies are providing a variety of biomolecular screening strategies from which to choose… 
1997
1997
Functional interactions between the thrombin receptor and the T-cell antigen receptor in human T-cell lines.
The proteolytically activated thrombin receptor (TR) is expressed by T lymphocytes, which suggests that thrombin may modulate T… 
1993
1993
Chromosomal assignment of the human thrombin receptor gene: localization to region q13 of chromosome 5.
A functional thrombin receptor (TR) structurally related to other members of the seven-transmembrane receptor family has been… 
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