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F2R wt Allele

Known as: CF2R, TR, HTR 
Human F2R wild-type allele is located within 5q13 and is approximately 20 kb in length. This allele, which encodes proteinase-activated receptor 1… Expand
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Human mesenchymal stem cells (MSCs) have increasingly been used as cellular vectors for the delivery of therapeutic genes to… Expand
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Highly Cited
2008
Highly Cited
2008
Astrocytes display excitability in the form of intracellular calcium concentration ([Ca2+]i) increases, but the signaling impact… Expand
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Highly Cited
2007
Highly Cited
2007
Myocardial ischemia/reperfusion (I/R) injury is partly mediated by thrombin. In support, the functional inhibition of thrombin… Expand
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Highly Cited
2003
Highly Cited
2003
Receptors for the serine protease thrombin and for lysophospholipids are coupled to G proteins and control a wide range of… Expand
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Highly Cited
2000
Highly Cited
2000
The recent identification of two new thrombin receptors, PAR3 and PAR4, led us to re-examine the basis for endothelial cell… Expand
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Highly Cited
2000
Highly Cited
2000
Protease-activated receptors 1 and 4 (PAR1 and PAR4) mediate thrombin signaling in human platelets. Whether these receptors are… Expand
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Highly Cited
2000
Highly Cited
2000
Thrombin activates platelets in an ordered sequence of events that includes shape change, increase in cytoplasmic Ca(2… Expand
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Highly Cited
2000
Highly Cited
2000
Platelet activation and aggregation are mediated by thrombin cleavage of the exodomain of the PAR1 receptor. The specificity of… Expand
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Highly Cited
1999
Highly Cited
1999
Although adenosine diphosphate (ADP), per se, is a weak platelet agonist, its role as a crucial cofactor in human blood platelet… Expand
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Highly Cited
1999
Highly Cited
1999
1. The law of Late Antiquity 2. Making the law 3. The construction of authority 4. The efficacy of law 5. In court 6. Crime and… Expand
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