F2R wt Allele

Known as: CF2R, TR, HTR 
Human F2R wild-type allele is located within 5q13 and is approximately 20 kb in length. This allele, which encodes proteinase-activated receptor 1… (More)
National Institutes of Health

Papers overview

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2010
2010
The protease-activated receptors (PAR1 and PAR2) are unusual G protein-coupled receptors that are activated by distinct serine… (More)
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2009
Highly Cited
2009
Human mesenchymal stem cells (MSCs) have increasingly been used as cellular vectors for the delivery of therapeutic genes to… (More)
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2008
Highly Cited
2008
Astrocytes display excitability in the form of intracellular calcium concentration ([Ca(2+)](i)) increases, but the signaling… (More)
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2008
2008
Thrombin is a multifunctional coagulation protease with pro- and anti-inflammatory vascular effects. We questioned whether… (More)
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2007
2007
Myocardial ischemia/reperfusion (I/R) injury is partly mediated by thrombin. In support, the functional inhibition of thrombin… (More)
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2003
Highly Cited
2003
Receptors for the serine protease thrombin and for lysophospholipids are coupled to G proteins and control a wide range of… (More)
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2000
2000
Skeletal muscle is known to be a target for the active metabolite of thyroid hormone, i.e., 3,5,3'-triiodothyronine (T(3)). T(3… (More)
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1999
Highly Cited
1999
Although adenosine diphosphate (ADP), per se, is a weak platelet agonist, its role as a crucial cofactor in human blood platelet… (More)
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1999
1999
We studied the actions of the human and murine proteinase-activated receptor 4 (PAR4) derived receptor-activating peptides (APs… (More)
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1997
1997
Thrombin's actions on platelets, macrophages, fibroblasts, and endothelial cells have prompted the hypothesis that thrombin may… (More)
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