Protease-Activated Receptor 1, human

Known as: Thrombin Receptor, Coagulation Factor II Receptor, PAR-1 
Proteinase-activated receptor 1 (425 aa, ~47 kDa) is encoded by the human F2R gene. This protein plays a role in thrombin-dependent G protein-coupled… (More)

Topic mentions per year

Topic mentions per year

1971-2018
051019712018

Papers overview

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2016
2016
Polymorphisms in platelet receptor genes may influence platelet function. This study aimed to assess the impact of five… (More)
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2014
2014
BACKGROUND The coagulation system becomes activated during progression and therapy of high-grade brain tumors. Triggering tissue… (More)
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2013
2013
Megakaryocyte (MK) development is critically informed by plasma membrane-localized receptors that integrate a multiplicity of… (More)
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2009
2009
Curcumin, a natural product isolated from the plant Curcuma longa, has a diverse range of molecular targets that influence… (More)
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2009
2009
Thrombin-activated factor 2 receptor (F2R) links thrombosis to inflammation modulating interleukin (IL)6 synthesis. We have… (More)
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2009
2009
BACKGROUND Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality… (More)
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2008
2008
As thrombin is proposed to be involved in stimulating myometrial contractility during labor and preterm labor, we aimed to… (More)
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Highly Cited
2006
Highly Cited
2006
To identify novel methylation-silenced genes in gastric cancers, we carried out a chemical genomic screening, a genome-wide… (More)
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2000
2000
n Drosophila melanogaster and Caenorhabditis elegans, development of the germ-line lineage depends upon cytoplasmic granules… (More)
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1994
1994
Thrombin receptor (TR) activation by alpha-thrombin requires proteolytic cleavage, although synthetic peptides modeled after the… (More)
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