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Epistasis, Genetic

Known as: Gene Interactions, Non-Allelic, Interactions, Epistatic Gene-Gene, Gene-Gene Interactions, Epistatic 
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose… 
National Institutes of Health

Related topics

Related topics

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Deviation, EpistaticGenes, ModifierMultifactorial Inheritanceaspects of radiation effects

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Genes, EpistaticGenes, Hypostatic

Papers overview

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2013
2013
Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci.
Hypertension, the most frequently diagnosed clinical condition world-wide, predisposes individuals to morbidity and mortality… 
Highly Cited
2011
Highly Cited
2011
High resolution ArrayCGH and expression profiling identifies PTPRD and PCDH17/PCH68 as tumor suppressor gene candidates in laryngeal squamous cell carcinoma
Many classical tumor suppressor genes (TSG) were identified by delineation of bi‐allelic losses called homozygous deletions. To… 
2008
2008
Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer.
BACKGROUND Allelic losses on chromosome 8p are common in prostate carcinoma, but it is not known exactly how they contribute to… 
Highly Cited
2007
Highly Cited
2007
Ant Species Differences Determined by Epistasis between Brood and Worker Genomes
Epistasis arising from physiological interactions between gene products often contributes to species differences, particularly… 
Highly Cited
2001
Highly Cited
2001
Evaluation of loss of heterozygosity/allelic imbalance scoring in tumor DNA.
2000
2000
Identification and fine mapping of a region showing a high frequency of allelic imbalance on chromosome 16q23.2 that corresponds to a prostate cancer susceptibility locus.
Linkage to a prostate cancer susceptibility locus was recently reported on chromosome 16q23. We now report a region exhibiting a… 
2000
2000
Mapping of Target Regions of Allelic Loss in Primary Breast Cancers to 1‐cM Intervals on Genomic Contigs at 6q21 and 6q25.3
Allelic losses on the long arm of human chromosome 6 are frequently observed in cancers of the ovary, prostate, and breast. To… 
Highly Cited
1999
Highly Cited
1999
Allelic loss on chromosome 6Q in primary prostate cancer
Molecular genetic analyses of human prostate cancer (CaP) has revealed frequent loss of specific chromosome regions suggesting… 
1999
1999
Consequences of cytonuclear epistasis and assortative mating for the genetic structure of hybrid populations
The effects of assortative mating and epistasis between interspecific nuclear and cytoplasmic genomes (cytonuclear… 
1996
1996
Allelic imbalance in mammary carcinomas induced by either 7,12‐dimethylbenz[a]anthracene or ionizing radiation in rats carrying genes conferring differential susceptibilities to mammary…
To identify and compare the genetic lesions associated with tumorigenesis in rats carrying the mammary carcinoma suppressor (MCS… 
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