Epistasis, Genetic

Known as: Gene Interactions, Non-Allelic, Interactions, Epistatic Gene-Gene, Gene-Gene Interactions, Epistatic 
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose… (More)
National Institutes of Health

Papers overview

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2010
2010
Gene-gene epistatic interactions likely play an important role in the genetic basis of many common diseases. Recently, machine… (More)
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2009
2009
BACKGROUND The IL23/IL17 pathway is pivotal in the development of chronic mucosal inflammation seen in Crohn's disease (CD… (More)
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2008
2008
The genetic basis of complex diseases is expected to be highly heterogeneous, with complex interactions among multiple disease… (More)
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Highly Cited
2007
Highly Cited
2007
Phylogenetic relationships among Pinus species from subgenus Strobus remain unresolved despite combined efforts based on nrITS… (More)
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Highly Cited
2004
Highly Cited
2004
Besides their use in mRNA expression profiling, oligonucleotide microarrays have also been applied to single-nucleotide… (More)
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Highly Cited
2004
Highly Cited
2004
The effects of mutations on phenotype and fitness may depend on the environment (phenotypic plasticity), other mutations (genetic… (More)
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Highly Cited
2003
Highly Cited
2003
We performed a genetic and epigenetic study of the hMLH1 and hMSH2 mismatch repair genes in resected primary tumors from 77 non… (More)
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Highly Cited
2000
Highly Cited
2000
Most human cancers are characterized by genomic instability, the accumulation of multiple genetic alterations and allelic… (More)
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Highly Cited
1996
Highly Cited
1996
It is well established that the progression to human cancer is characterized by the evolution of clones of cells with accumulated… (More)
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Highly Cited
1994
Highly Cited
1994
THE Wnt genes encode conserved secreted proteins that play a role in normal development and tumorigenesis1,2. Little is known… (More)
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