• Publications
  • Influence
The Increasing Dominance of Teams in Production of Knowledge
We have used 19.9 million papers over 5 decades and 2.1 million patents to demonstrate that teams increasingly dominate solo authors in the production of knowledge. Research is increasingly done inExpand
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Computational Prediction of Host-Parasite Protein Interactions between P. falciparum and H. sapiens
  • S. Wuchty
  • Biology, Medicine
  • PloS one
  • 17 November 2011
To obtain candidates of interactions between proteins of the malaria parasite Plasmodium falciparum and the human host, homologous and conserved interactions were inferred from various sources ofExpand
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Multi-University Research Teams: Shifting Impact, Geography, and Stratification in Science
This paper demonstrates that teamwork in science increasingly spans university boundaries, a dramatic shift in knowledge production that generalizes across virtually all fields of science,Expand
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Controllability in protein interaction networks
  • S. Wuchty
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 28 April 2014
Significance In human and yeast protein interaction datasets we determined minimum dominating sets (MDSets), proteins that play a role in the control of the underlying interaction webs. Such proteinsExpand
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The binary protein-protein interaction landscape of Escherichia coli
Efforts to map the Escherichia coli interactome have identified several hundred macromolecular complexes, but direct binary protein-protein interactions (PPIs) have not been surveyed on a largeExpand
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Evolutionary cores of domain co-occurrence networks
BackgroundThe modeling of complex systems, as disparate as the World Wide Web and the cellular metabolism, as networks has recently uncovered a set of generic organizing principles: Most of theseExpand
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Cancer Missense Mutations Alter Binding Properties of Proteins and Their Interaction Networks
Many studies have shown that missense mutations might play an important role in carcinogenesis. However, the extent to which cancer mutations might affect biomolecular interactions remains unclear.Expand
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Regulatory Hotspots in the Malaria Parasite Genome Dictate Transcriptional Variation
The determinants of transcriptional regulation in malaria parasites remain elusive. The presence of a well-characterized gene expression cascade shared by different Plasmodium falciparum strainsExpand
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New online ecology of adversarial aggregates: ISIS and beyond
TLDR
We provide a mathematical theory that describes an ecology evolving on a daily time scale that drives online support for adversarial groups such as Islamic State (ISIS) and provide predictive power and potential countermeasures. Expand
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Human Communication Dynamics in Digital Footsteps: A Study of the Agreement between Self-Reported Ties and Email Networks
TLDR
We analyzed the correspondence between self-reported social network data and email communication data with the objective of identifying the dynamics in e-communication that correlate with a person's perception of a significant network tie. Expand
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